Evidence map›Paper›PMID 32542535›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2020

Tert-Butyl Hydroperoxide Stimulated Apoptosis Independent of Prostaglandin E

Rita Loch-Caruso, Cassandra S Korte, Kelly A Hogan, Sarah Liao, Craig Harris

Open access · greenAbstract read
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rita Loch-CarusoDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA. rlc@umich.edu.ORCID 0000-0002-5993-2799
Cassandra S KorteDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA.ORCID 0000-0002-2156-3975
Kelly A HoganDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA.ORCID 0000-0002-4274-0280
Sarah LiaoDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA.
Craig HarrisDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA.
University of Michigan · USLynn University · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Research Experiences and Training Coordination CoreP42ES017198 · NIEHS · NORTHEASTERN UNIVERSITY · PI HARRIS, SEAN M · 2010 to 2024
$38.6M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
ENVIRONMENTAL TOXICOLOGY PRE/POST DOCTORAL RES.TRAININGT32ES007062 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin Adam Colacino · 1985 to 2026
$10.5M
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NIEHS NIH HHS P30 ES017885NIEHS NIH HHS P42 ES017198NIEHS NIH HHS T32 ES007062
6 · The paper itself

Abstract

Significant gaps exist in our knowledge of how cellular redox status, sometimes referred to as oxidative stress, impacts placental trophoblasts. The present study used tert-butyl hydroperoxide (TBHP) as a known generator of reactive oxygen species (ROS) in the extravillous trophoblast cell line HTR-8/SVneo to examine the role of cellular redox disruption of prostaglandin E

Indexed as

ApoptosisCell LineDinoprostoneFemaleHumansInterleukin-6PlacentaPregnancyReactive Oxygen Speciestert-ButylhydroperoxideTrophoblastsDinoprostoneInterleukin-6Reactive Oxygen Speciestert-ButylhydroperoxideApoptosisOxidative stressProstaglandinsReactive oxygen speciesTrophoblasts

Identifiers

PMID32542535
PMCPMC7529854
OpenAlexW3034966476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.