Evidence map›Paper›PMID 32542524›Full record

ReviewJournal of neurology2021

New strategies for managing adult gliomas.

Alastair J Kirby, Gerald T Finnerty

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alastair J KirbyDepartment of Basic and Clinical Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.ORCID http://orcid.org/0000-0003-1525-0902
Gerald T FinnertyDepartment of Basic and Clinical Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK. gerald.finnerty@kcl.ac.uk.ORCID http://orcid.org/0000-0003-1082-0128

Funding

Medical Research Council 1847459Medical Research Council MR/N013700/1Psychiatry Research Trust 0A/Finnerty
6 · The paper itself

Abstract

Gliomas are hard to treat. Their prognosis has improved little over the past few decades. Fundamental therapeutic challenges such as treatment resistance, malignant progression, and tumour recurrence persist. New strategies are needed to advance the management and treatment of gliomas. Here, we focus on where those new strategies could emerge. We consider how recent advances in our understanding of the biology of adult gliomas are informing new approaches to their treatment.

Indexed as

Brain NeoplasmsGliomaAdultHumansNeoplasm Recurrence, LocalPrognosisCancerGlioblastomaMalignant progressionSeizureTreatment resistanceTumour recurrence

Identifiers

PMID32542524
PMCPMC8463358

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.