Evidence map›Paper›PMID 32542504›Full record

ArticleOphthalmology and therapy2020

A Case of Early Keratoconus Associated with Eye Rubbing in a Young Child.

Victoria Dimacali, Miltos Balidis, Aspasia Adamopoulou, Athina Kozei, Nikolaos Kozeis

Open access · goldAbstract read
In one paragraph

Article in Ophthalmology and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Short-term digital ocular massage may weaken corneal biomechanics.Frontiers in bioengineering and biotechnology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. The Underlying Relationship between Keratoconus and Down Syndrome.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Victoria DimacaliOphthalmica Institute of Ophthalmology and Microsurgery, Thessaloniki, Greece.
Miltos BalidisOphthalmica Institute of Ophthalmology and Microsurgery, Thessaloniki, Greece.
Aspasia AdamopoulouOphthalmica Institute of Ophthalmology and Microsurgery, Thessaloniki, Greece.
Athina KozeiOphthalmica Institute of Ophthalmology and Microsurgery, Thessaloniki, Greece.
Nikolaos KozeisOphthalmica Institute of Ophthalmology and Microsurgery, Thessaloniki, Greece. kozeis@paidoofthamiatros.gr.
Athens Eye Hospital · GRMakati Medical Center · PHUniversity of Nicosia · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKeratoconus usually presents during puberty and is considered rare in young children.

methodsCase report with clinical findings and computerized corneal tomography.

resultsWe report the case of an 8-year-old girl with early bilateral keratoconus who presented with allergic conjunctivitis and persistent eye rubbing. Although our patient did not exhibit steep keratometry, early cones and inferotemporal thinnest corneal thicknesses were detected in both eyes using Scheimpflug imaging (Oculus GmbH Pentacam, Wetzlar, Germany). Belin/Ambrósio total D values were 1.85 on the right and 2.11 on the left. Improvement in best-corrected visual acuity was noted after treatment of allergic eye disease, and corneal tomographic findings remained stable 4 months after initial consult.

conclusionThis is a case of early diagnosed keratoconus in a young patient. Diagnosis of this condition in young children is challenging, as these patients are less likely to report visual complaints, and clinical examination is usually unremarkable. Keratoconus screening should be considered in children with atopy and eye rubbing behavior regardless of age, even in those with no other associated pathology and with negative family history.

Indexed as

Allergic conjunctivitisAtopyCorneal tomographyEye rubbingKeratoconusPediatric keratoconus

Identifiers

PMID32542504
PMCPMC7406581
OpenAlexW3034570015

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.