Evidence map›Paper›PMID 32542441›Full record

SynthesisBehavior research methods2020

Multiple moderator meta-analysis using the R-package Meta-CART.

Xinru Li, Elise Dusseldorp, Xiaogang Su, Jacqueline J Meulman

Abstract readMeta-Analysis
In one paragraph

Synthesis in Behavior research methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Enhancing Weight Loss Programs: A Meta-Analysis of Financial Incentives and Behavior Change Techniques.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  9. Review
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  13. Molecular prevalence ofOne health (Amsterdam, Netherlands) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinru LiMathematical Institute, Leiden University, P.O. Box 9512, 2300, RA, Leiden, The Netherlands.ORCID 0000-0001-6859-2311
Elise DusseldorpInstitute of Psychology, Leiden University, P.O. Box 9555, 2300, RB, Leiden, The Netherlands. elise.dusseldorp@fsw.leidenuniv.nl.
Xiaogang SuDepartment of Mathematical Sciences, University of Texas at El Paso, Austin, TX, 78712, USA.
Jacqueline J MeulmanMathematical Institute, Leiden University, P.O. Box 9512, 2300, RA, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In meta-analysis, heterogeneity often exists between studies. Knowledge about study features (i.e., moderators) that can explain the heterogeneity in effect sizes can be useful for researchers to assess the effectiveness of existing interventions and design new potentially effective interventions. When there are multiple moderators, they may amplify or attenuate each other's effect on treatment effectiveness. However, in most meta-analysis studies, interaction effects are neglected due to the lack of appropriate methods. The method meta-CART was recently proposed to identify interactions between multiple moderators. The analysis result is a tree model in which the studies are partitioned into more homogeneous subgroups by combinations of moderators. This paper describes the R-package metacart, which provides user-friendly functions to conduct meta-CART analyses in R. This package can fit both fixed- and random-effects meta-CART, and can handle dichotomous, categorical, ordinal and continuous moderators. In addition, a new look ahead procedure is presented. The application of the package is illustrated step-by-step using diverse examples.

Indexed as

Research DesignHumansTreatment OutcomeCARTComputer softwareFixed effectHeterogeneityInteraction between moderatorsMeta-analysisRandom effects

Identifiers

PMID32542441
PMCPMC7725699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.