Evidence map›Paper›PMID 32542257›Full record

ArticleThe Analyst2020

Dynamic single-cell intracellular pH sensing using a SERS-active nanopipette.

Jing Guo, Alberto Sesena Rubfiaro, Yanhao Lai, Joseph Moscoso, Feng Chen, Yuan Liu, Xuewen Wang, Jin He

Abstract read
In one paragraph

Article in The Analyst, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Surface-enhanced Raman scattering: An emerging tool for sensing cellular function.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
  13. Plasmonic Au@Ag@mSiOACS applied materials & interfaces · 2021
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing GuoDepartment of Physics, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA. jinhe@fiu.edu.
Alberto Sesena Rubfiaro
Yanhao Lai
Joseph Moscoso
Feng Chen
Yuan Liu
Xuewen Wang
Jin He

Funding

Trinucleotide Repeat Instability via DNA Damage and RepairR01ES023569 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI LIU, YUAN · 2014 to 2018
$1.6M
NIEHS NIH HHS R01 ES023569
6 · The paper itself

Abstract

Glass nanopipettes have shown promise for applications in single-cell manipulation, analysis, and imaging. In recent years, plasmonic nanopipettes have been developed to enable surface-enhanced Raman spectroscopy (SERS) measurements for single-cell analysis. In this work, we developed a SERS-active nanopipette that can be used to perform long-term and reliable intracellular analysis of single living cells with minimal damage, which is achieved by optimizing the nanopipette geometry and the surface density of the gold nanoparticle (AuNP) layer at the nanopipette tip. To demonstrate its ability in single-cell analysis, we used the nanopipette for intracellular pH sensing. Intracellular pH (pH

Indexed as

GoldMetal NanoparticlesHeLa CellsHumansHydrogen-Ion ConcentrationSpectrum Analysis, RamanGold

Identifiers

PMID32542257
PMCPMC7425357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.