ArticleNature chemistry2020
A site-selective amination catalyst discriminates between nearly identical C-H bonds of unsymmetrical disubstituted alkenes.
Article in Nature chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 97 citations in OpenAlex.
- Unified Synthesis Platform for 1,2,3-Trisubstituted Cyclopentadienyl Ligands Decouples Sterics from Electronics.Journal of the American Chemical Society · 2026Article
- Emerging Applications of Thiol-Based Catalysts in Hydrogen Atom Transfer Reactions: A Comprehensive Review.Molecules (Basel, Switzerland) · 2025Review
- C(spJournal of the American Chemical Society · 2025Article
- Allylic Amination of Alkenyl Alcohols: Simultaneous Control of Chemoselectivity and Enantioselectivity in Nitrene Transfer Using Ion-Paired Catalysts.ACS catalysis · 2025Article
- Catalytic Amino Group Transfer Reactions Mediated by Photoinduced Nitrene Formation from Rhodium-Hydroxamates.Angewandte Chemie (International ed. in English) · 2025Article
- Halide Perovskite Induces Halogen/Hydrogen Atom Transfer (XAT/HAT) for Allylic C-H Amination.Angewandte Chemie (International ed. in English) · 2025Article
- Photoinduced Pd-Catalyzed Direct Sulfonylation of Allylic C-H Bonds.Angewandte Chemie (International ed. in English) · 2025Article
- Rhodium(III)-Catalyzed Remote Hydroamidation of Internal Alkenes via Chain Walking.ACS catalysis · 2023Article
- Practical synthesis of allylic aminesChemical science · 2023Article
- Allylic Amination of Highly Substituted Alkenes Enabled by Photoredox Catalysis and Cu(II)-Mediated Radical-Polar Crossover.Organic letters · 2023Article
- Metalloradical approach for concurrent control in intermolecular radical allylic C-H amination.Nature chemistry · 2023Article
- Asymmetric intermolecular allylic C-H amination of alkenes with aliphatic amines.Science (New York, N.Y.) · 2022Article
- Rh(III)-catalyzed Intra- and Intermolecular 3,4-Difunctionalization of 1,3-DienesACS catalysis · 2022Article
- Allylic C-H amination cross-coupling furnishes tertiary amines by electrophilic metal catalysis.Science (New York, N.Y.) · 2022Article
- Stereoretentive and regioselective selenium-catalyzed intermolecular propargylic C-H amination of alkynes.Chemical science · 2022Article
- Metal-free allylic C-H nitrogenation, oxygenation, and carbonation of alkenes by thianthrenation.Chemical science · 2022Article
- Site-Selective α-C-H Functionalization of Trialkylamines via Reversible Hydrogen Atom Transfer Catalysis.Journal of the American Chemical Society · 2021Article
- Diastereoselective Three-Component 3,4-Amino Oxygenation of 1,3-Dienes Catalyzed by a Cationic Heptamethylindenyl Rhodium(III) Complex.Journal of the American Chemical Society · 2021Article
- A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(spAngewandte Chemie (International ed. in English) · 2021Article
- Late-Stage Intermolecular Allylic C-H Amination.Journal of the American Chemical Society · 2021Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
C-H activation reactions enable chemists to unveil new retrosynthetic disconnections and streamline conventional synthetic approaches. A long-standing challenge in C-H activation is the inability to distinguish electronically and sterically similar C-H bonds. Although numerous synergistic combinations of transition-metal complexes and chelating directing groups have been utilized to distinguish C-H bonds, undirected regioselective C-H functionalization strategies remain elusive. Here we report a regioselective C-H activation/amination reaction of various unsymmetrical dialkyl-substituted alkenes. The regioselectivity of C-H activation is correlated to the electronic properties of allylic C-H bonds indicated by the corresponding
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