Evidence map›Paper›PMID 32541610›Full record

ArticleSpine2020

Preoperative Factors Predict Postoperative Trajectories of Pain and Disability Following Surgery for Degenerative Lumbar Spinal Stenosis.

Jeffrey J Hébert, Edward Abraham, Niels Wedderkopp, Erin Bigney, Eden Richardson, Mariah Darling, Hamilton Hall, Charles G Fisher, Y Raja Rampersaud, Kenneth C Thomas and 11 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Spine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. The prevalence of depression in degenerative spine disease patients: A systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Pooled it
  3. Preoperative multifidus activation during movement and low back pain worsening after lumbar spinal stenosis surgery: a prospective observational study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  17. Preoperative fatty infiltration of paraspinal muscles assessed by MRI is associated with less improvement of leg pain 2 years after surgery for lumbar spinal stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 15 institutions in 3 countries.

Jeffrey J HébertFaculty of Kinesiology, University of New Brunswick, New Brunswick, Canada.
Edward AbrahamCanada East Spine Centre, Saint John, New Brunswick, Canada.
Niels WedderkoppDepartment of Regional Health Research, University of Southern Denmark, Denmark.
Erin BigneyCanada East Spine Centre, Saint John, New Brunswick, Canada.
Eden RichardsonCanada East Spine Centre, Saint John, New Brunswick, Canada.
Mariah DarlingCanada East Spine Centre, Saint John, New Brunswick, Canada.
Hamilton HallUniversity of Toronto, Toronto, Canada.
Charles G FisherCombined Neurosurgical and Orthopedic Spine Program, Department of Orthopedic Surgery, Blusson Spinal Cord Centre, University of British Columbia, Vancouver, Canada.
Y Raja RampersaudDivision of Orthopaedic Surgery, Toronto Western Hospital, Toronto, Canada.
Kenneth C ThomasSection of Orthopedic Surgery Spine Program, Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
W Bradley JacobsDivision of Neurosurgery-Spine Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Michael JohnsonDepartments of Orthopedics and Neurosurgery, University of Manitoba, Manitoba, Canada.
Jérôme PaquetDivision of Neurosurgery, Department of Surgery, CHU de Quebec-Universite Laval, Quebec City, Quebec, Canada.
Najmedden AttabibCanada East Spine Centre, Saint John, New Brunswick, Canada.
Peter JarzemMcGill Scoliosis and Spine Research Group, Montreal, Quebec, Canada.
Eugene K WaiDepartment of Surgery, University of Ottawa, Ottawa, ON, Canada.
Parham RasoulinejadLondon Health Sciences Center, London, ON, Canada.
Henry AhnUniversity of Toronto Spine Program, Toronto, Ontario, Canada.
Andrew NatarajDivision of Neurosurgery, Faculty of Medicine and Dentistry, Department of Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada.
Alexandra StrattonDepartment of Surgery, University of Ottawa, Ottawa, ON, Canada.
Neil MansonCanada East Spine Centre, Saint John, New Brunswick, Canada.
Canada East Spine Centre · CAHorizon Health Network · CAUniversity of Calgary · CAUniversity of Ottawa · CAUniversity of Toronto · CADalhousie University · CALondon Health Sciences Centre · CAMcGill University · CAMurdoch University · AUToronto Western Hospital · CAUniversité Laval · CAUniversity of Alberta · CAUniversity of British Columbia · CAUniversity of Manitoba · CAUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designLongitudinal analysis of prospectively collected data.

objectiveInvestigate potential predictors of poor outcome following surgery for degenerative lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA: LSS is the most common reason for an older person to undergo spinal surgery, yet little information is available to inform patient selection.

methodsWe recruited LSS surgical candidates from 13 orthopedic and neurological surgery centers. Potential outcome predictors included demographic, health, clinical, and surgery-related variables. Outcome measures were leg and back numeric pain rating scales and Oswestry disability index scores obtained before surgery and after 3, 12, and 24 postoperative months. We classified surgical outcomes based on trajectories of leg pain and a composite measure of overall outcome (leg pain, back pain, and disability).

resultsData from 529 patients (mean [SD] age = 66.5 [9.1] yrs; 46% female) were included. In total, 36.1% and 27.6% of patients were classified as experiencing a poor leg pain outcome and overall outcome, respectively. For both outcomes, patients receiving compensation or with depression/depression risk were more likely, and patients participating in regular exercise were less likely to have poor outcomes. Lower health-related quality of life, previous spine surgery, and preoperative anticonvulsant medication use were associated with poor leg pain outcome. Patients with ASA scores more than two, greater preoperative disability, and longer pain duration or surgical waits were more likely to have a poor overall outcome. Patients who received preoperative chiropractic or physiotherapy treatment were less likely to report a poor overall outcome. Multivariable models demonstrated poor-to acceptable (leg pain) and excellent (overall outcome) discrimination.

conclusionApproximately one in three patients with LSS experience a poor clinical outcome consistent with surgical non-response. Demographic, health, and clinical factors were more predictive of clinical outcome than surgery-related factors. These predictors may assist surgeons with patient selection and inform shared decision-making for patients with symptomatic LSS. LEVEL OF EVIDENCE: 2.

Indexed as

Persons with DisabilitiesAdultAgedAged, 80 and overBack PainFemaleFollow-Up StudiesHumansLongitudinal StudiesLumbar VertebraeMaleMiddle AgedNeurosurgical ProceduresPain MeasurementPostoperative ComplicationsPreoperative Care

Identifiers

PMID32541610
PMCPMC7547903
OpenAlexW3035332943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.