Evidence map›Paper›PMID 32541456›Full record

ArticleMedicine2020

A comprehensive assessment of single nucleotide polymorphisms associated with pancreatic cancer risk: A protocol for systematic review and network meta-analysis.

Zhuo-Miao Ye, Li-Juan Li, Jing-Hui Zheng, Chi Zhang, Yun-Xin Lu, Youming Tang

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhuo-Miao YeRuikang School of Clinical Medicine, Guangxi University of Chinese Medicine.
Li-Juan LiThe First Clinical Faculty of Guangxi University of Chinese Medicine.
Jing-Hui ZhengDepartment of Cardiology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning.
Chi ZhangGraduate School, Guangxi University of Chinese Medicine.
Yun-Xin LuDepartment of Oncology.
Youming TangDepartment of Gastroenterology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Guangxi University of Chinese Medicine · CNGuangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSingle nucleotide polymorphisms (SNPs) have been inconsistently associated with pancreatic cancer (PC) risk. This meta-analysis aimed to synthesize relevant data on SNPs associated with PC.

methodsDatabases were searched to identify association studies of SNPs and PC published through January 2020 from the databases of PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure, the Chinese Science and Technology Periodical Database (VIP) and Wanfang databases. Network meta-analysis and Thakkinstian algorithm were used to select the most appropriate genetic model, along with false positive report probability (FPRP) for noteworthy associations. The methodological quality of data was assessed based on the STREGA statement Stata 14.0 will be used for systematic review and meta-analysis.

resultsThis study will provide a high-quality evidence to find the SNP most associated with pancreatic cancer susceptibility and the best genetic model.

conclusionsThis study will explore which SNP is most associated with pancreatic cancer susceptibility.Registration: INPLASY202040023.

Indexed as

AlgorithmsCase-Control StudiesChinaFalse Positive ReactionsFemaleGenetic Predisposition to DiseaseHumansMaleNetwork Meta-Analysis as TopicPancreatic NeoplasmsPolymorphism, Single NucleotideRiskSensitivity and SpecificitySystematic Reviews as Topic

Identifiers

PMID32541456
PMCPMC7302655
OpenAlexW3031714824

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.