Evidence map›Paper›PMID 32541002›Full record

ArticleDevelopment (Cambridge, England)2020

Lisa D Urness, Xiaofen Wang, Chaoying Li, Rolen M Quadros, Donald W Harms, Channabasavaiah B Gurumurthy, Suzanne L Mansour

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. SHANK2 establishes auditory hair bundle architecture essential for mammalian hearing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lisa D UrnessDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Xiaofen WangDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Chaoying LiDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Rolen M QuadrosMouse Genome Engineering Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Donald W HarmsMouse Genome Engineering Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Channabasavaiah B GurumurthyMouse Genome Engineering Core Facility, Vice Chancellor for Research Office, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-8022-4033
Suzanne L MansourDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA suzi.mansour@genetics.utah.edu.ORCID 0000-0001-9040-302X
University of Utah · USUniversity of Nebraska Medical Center · US

Funding

Signals Integrating Cellular Dynamics to Sculpt the Inner Ear (A1)R01DC011819 · NIDCD · UNIVERSITY OF UTAH · PI MANSOUR, SUZANNE L, SCHOENWOLF, GARY C · 2012 to 2016
$2.3M
Regulation of auditory supporting cell differentiation and plasticityR01DC014470 · NIDCD · UNIVERSITY OF UTAH · PI MANSOUR, SUZANNE L · 2016 to 2020
$1.6M
New mouse models for inducible cell-specific ablationR21DC014779 · NIDCD · UNIVERSITY OF UTAH · PI MANSOUR, SUZANNE L · 2015 to 2016
$410k
NIDCD NIH HHS R01 DC011819NIDCD NIH HHS R01 DC014470NIDCD NIH HHS R21 DC014779
6 · The paper itself

Abstract

Pan-otic CRE drivers enable gene regulation throughout the otic placode lineage, comprising the inner ear epithelium and neurons. However, intersection of extra-otic gene-of-interest expression with the CRE lineage can compromise viability and impede auditory analyses. Furthermore, extant pan-otic CREs recombine in auditory and vestibular brain nuclei, making it difficult to ascribe resulting phenotypes solely to the inner ear. We have previously identified

Indexed as

AnimalsAntiportersFibroblast Growth Factor 10Fibroblast Growth Factor 3Fibroblast Growth Factor 8Gene Expression Regulation, DevelopmentalMiceReceptor, Fibroblast Growth Factor, Type 2Sulfate TransportersAntiportersFgf10 protein, mouseFgf3 protein, mouseFgf8 protein, mouseFibroblast Growth Factor 10Fibroblast Growth Factor 3Fibroblast Growth Factor 8Receptor, Fibroblast Growth Factor, Type 2Slc26a9 protein, mouseSulfate TransportersCre driverFgf10 conditional mutantFgf8 conditional mutantFGFR2b ligand trapHearingInner ear

Identifiers

PMID32541002
PMCPMC7358128
OpenAlexW3035261577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.