Evidence map›Paper›PMID 32540979›Full record

ArticleAntimicrobial agents and chemotherapy2020

Efficacy of Guanabenz Combination Therapy against Chronic Toxoplasmosis across Multiple Mouse Strains.

Jennifer Martynowicz, J Stone Doggett, William J Sullivan

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  8. Structure-activity relationships ofExpert opinion on drug discovery · 2022
    Article
  9. The determinants regulatingFrontiers in microbiology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Frontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennifer MartynowiczDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
J Stone DoggettDivision of Infectious Diseases, Oregon Health and Science University School of Medicine, Portland, Oregon, USA.
William J SullivanDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA wjsulliv@iu.edu.ORCID 0000-0003-1823-8642
Indiana University School of MedicineOregon Health & Science University · US

Funding

Immunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0M
Translational control during stage conversion of Toxoplasma, an opportunistic infection of HIV/AIDSR01AI124723 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SULLIVAN, WILLIAM J, WEK, RONALD C · 2016 to 2020
$2.0M
Eradicating latent toxoplasmosisR21AI150616 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SULLIVAN, WILLIAM J · 2020 to 2021
$420k
Novel Therapeutic Strategies for ELQ-422, a preclinical Toxoplasmosis Drug CandidateI01BX004522 · VA · PORTLAND VA MEDICAL CENTER · PI Joseph Stone Doggett · 2019 to 2026
–
Development of the potent anti-malarial and anti-Toxoplasma drug, ELQ-316IK2BX002440 · VA · PORTLAND VA MEDICAL CENTER · PI DOGGETT, JOSEPH STONE · 2014 to 2018
–
BLRD VA I01 BX004522BLRD VA IK2 BX002440NIAID NIH HHS R01 AI124723NIAID NIH HHS R21 AI150616NIAID NIH HHS T32 AI060519
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ToxoplasmaToxoplasmosisToxoplasmosis, AnimalAnimalsGuanabenzMiceMice, Inbred BALB CMice, Inbred C57BLGuanabenzantimicrobial combinationsdrug developmentguanabenzhost-pathogen interactionsparasitesToxoplasma

Identifiers

PMID32540979
PMCPMC7449173
OpenAlexW3034815647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.