Evidence map›Paper›PMID 32540932›Full record

ArticleJournal of bacteriology2020

YejM Controls LpxC Levels by Regulating Protease Activity of the FtsH/YciM Complex of Escherichia coli.

Daniel Nguyen, Keilen Kelly, Nan Qiu, Rajeev Misra

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Exploring the Link Between Biotin Metabolism andPathogens (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. A periplasmic protein modulates the proteolysis of peptidoglycan hydrolases to maintain cell wall homeostasis inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Dual function of LapB (YciM) in regulatingProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Dual function of LapB (YciM) in regulatingProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Signaling through theJournal of bacteriology · 2024
    Article
  16. Suppressors ofInternational journal of molecular sciences · 2023
    Article
  17. A role for the Gram-negative outer membrane in bacterial shape determination.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Lipopolysaccharides: Regulated Biosynthesis and Structural Diversity.International journal of molecular sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daniel NguyenSchool of Life Sciences, Arizona State University, Tempe, Arizona, USA.
Keilen KellySchool of Life Sciences, Arizona State University, Tempe, Arizona, USA.
Nan QiuDepartment of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA.
Rajeev MisraSchool of Life Sciences, Arizona State University, Tempe, Arizona, USA rajeev.misra@asu.edu.ORCID 0000-0001-8007-420X
Arizona State University · USScripps Research Institute · US

Funding

Detailed mapping of drug binding and translocation sites in the AcrB pump proteinR21AI117150 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MISRA, RAJEEV · 2016 to 2017
$408k
NIAID NIH HHS R21 AI117150
6 · The paper itself

Abstract

LpxC is a deacetylase that catalyzes the first committed step of lipid A biosynthesis in

Indexed as

AmidohydrolasesATP-Dependent ProteasesDrug Resistance, BacterialEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialLipopolysaccharidesMembrane ProteinsAmidohydrolasesATP-Dependent ProteasesEscherichia coli ProteinsFtsH protein, E coliLipopolysaccharidesMembrane ProteinsUDP-3-O-acyl-N-acetylglucosamine deacetylaseYciM protein, E coliYejM protein, E coliEscherichia coliFtsH proteaselipid homeostasislipopolysaccharideLpxCYciMYejM

Identifiers

PMID32540932
PMCPMC7925073
OpenAlexW3035111211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.