SynthesisBreast (Edinburgh, Scotland)2020
Diagnostic accuracy of contrast-enhanced spectral mammography for breast lesions: A systematic review and meta-analysis.
Synthesis in Breast (Edinburgh, Scotland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic accuracy of contrast-enhanced mammography in evaluating breast cancer response to neoadjuvant therapy: a systematic review and meta-analysis.La Radiologia medica · 2026Pooled it
- Pooled it
- Predictive deep learning model based on contrast-enhanced mammography for breast cancer diagnosis: a pilot study.BJR artificial intelligence · 2026Article
- Explainable Deep Learning for Breast Lesion Classification in Digital and Contrast-Enhanced Mammography.Diagnostics (Basel, Switzerland) · 2025Article
- Does Contrast-Enhanced Mammography Outperform Digital Breast Tomosynthesis for Detection and Characterization of Breast Lesions or Vice Versa?Indian journal of surgical oncology · 2025Article
- Factors Influencing Background Parenchymal Enhancement in Contrast-Enhanced Mammography Images.Diagnostics (Basel, Switzerland) · 2024Article
- Contrast-enhanced mammography versus conventional imaging in women recalled from breast cancer screening (RACER trial): a multicentre, open-label, randomised controlled clinical trial.The Lancet regional health. Europe · 2024Article
- Breast masses with rim enhancement on contrast-enhanced mammography: morphological and enhancement features for diagnosis and differentiation of benign and malignant.The British journal of radiology · 2024Article
- State-of-the-art for contrast-enhanced mammography.The British journal of radiology · 2024Review
- Association and predictive value of contrast‑enhanced ultrasound features with axillary lymph node metastasis in primary breast cancer.Oncology letters · 2024Article
- Dynamic contrast-enhanced mammography and breast MRI in the diagnosis of breast cancer and detection of tumor size.Turkish journal of medical sciences · 2024Article
- Comparative Evaluation of Contrast-Enhanced Spectral Mammography and Digital Breast Tomosynthesis for Diagnosing and Treating Breast Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Inter-reader agreement of breast magnetic resonance imaging and contrast-enhanced mammography in breast cancer diagnosis: a multi-reader retrospective study.Breast cancer research and treatment · 2023Article
- [Use of contrast-enhanced mammography for diagnosis of breast cancer].Radiologie (Heidelberg, Germany) · 2023Review
- Diagnostic Performance of Contrast-Enhanced Digital Mammography versus Conventional Imaging in Women with Dense Breasts.Diagnostics (Basel, Switzerland) · 2023Article
- Background enhancement in contrast-enhanced spectral mammography (CESM): are there qualitative and quantitative differences between imaging systems?European radiology · 2023Article
- How Radiomics Can Improve Breast Cancer Diagnosis and Treatment.Journal of clinical medicine · 2023Review
- Overview of Artificial Intelligence in Breast Cancer Medical Imaging.Journal of clinical medicine · 2023Review
- Comparing the Diagnostic Performance of Contrast-Enhanced Mammography and Breast MRI: a Systematic Review and Meta-Analysis.Journal of Cancer · 2023Review
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer diagnosis and staging is based on mammography, ultrasound, and magnetic resonance imaging (MRI). Contrast enhanced spectral mammography (CESM) has gained momentum as an innovative and clinically useful method for breast assessment. CESM is based on abnormal enhancement of neoplastic tissue compared to surrounding breast tissue. We performed a systematic review of prospective trial to evaluate its diagnostic performance, following standard PRISMA-DTA. We used a bivariate random-effects regression approach to obtain summary estimates of both sensitivity and specificity of CESM. 8 studies published between 2003 and 2019 were included in the meta-analysis for a total of 945 lesions. The summary area under the curve obtained from all the study was 89% [95% CI 86%-91%], with a sensitivity of 85% [95% CI 73%-93%], and a specificity of 77% [95% CI 60%-88%]. With a pre-test probability of malignancy of 57% a positive finding at CESM gives a post-test probability of 83% while a negative finding a post-test probability of 20%. CESM shows a suboptimal sensitivity and specificity in the diagnosis of breast cancer in a selected population, and at present time, it could be considered only as a possible alternative test for breast lesions assessment when mammography and ultrasound are not conclusive or MRI is contraindicated or not available.
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