Evidence map›Paper›PMID 32539817›Full record

ArticleBMC public health2020

What are the sociodemographic and gender determinants of non-fatal self-harm in older adult users and non-users of antidepressants? A national population-based study.

Khedidja Hedna, Johan Fastbom, Ingmar Skoog, Gunnel Hensing, Margda Waern

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Khedidja HednaCenter for Ageing and Health (Age Cap), Department of Psychiatry and Neurochemistry, Gothenburg University, SE-413 45, Gothenburg, Sweden. Khedidja.hedna@neuro.gu.se.ORCID http://orcid.org/0000-0002-4642-4592
Johan FastbomAging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Ingmar SkoogCenter for Ageing and Health (Age Cap), Department of Psychiatry and Neurochemistry, Gothenburg University, SE-413 45, Gothenburg, Sweden.
Gunnel HensingSection of Epidemiology and Social Medicine, Department of Public Health and Community Medicine at Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Margda WaernCenter for Ageing and Health (Age Cap), Department of Psychiatry and Neurochemistry, Gothenburg University, SE-413 45, Gothenburg, Sweden.
Sahlgrenska University Hospital · SEStatisticon (Sweden) · SEStockholm University · SEUniversity of Gothenburg · SE

Funding

ALFGBG 715841Forskningsrådet om Hälsa, Arbetsliv och Välfärd 2016-07097Söderström-König Foundation 844351Vetenskapsrådet 2016-01590
6 · The paper itself

Abstract

backgroundLate-life self-harm (SH) is often linked to depression. However, very few studies have explored the role of other factors and their interaction with depression in the occurrence of late-life SH. The objective of this research was to examine sociodemographic and gender factors associated with non-fatal SH, in older adults with and without antidepressant therapy.

methodsWe used national longitudinal register data from a total cohort of all Swedish residents aged ≥75 years between 2006 and 2014 (N = 1,413,806). Using personal identity numbers, we linked individuals' data from numerous national registers. We identified all those with at least one episode of non-fatal self-harm (regardless of level of intent to die) and matched 50 controls to each case. A nested case-control design was used to investigate sociodemographic factors associated with non-fatal SH in the total cohort and among antidepressant users and non-users. Risk factors were analysed in adjusted conditional logistic regression models for the entire cohort and by gender.

resultsIn all, 2242 individuals had at least one episode of a non-fatal SH (980 men and 1262 women). Being unmarried was a risk factor for non-fatal SH in men but not in women. Among users of antidepressants, higher non-fatal SH risk was observed in those born outside the Nordic countries (IRR: 1.44; 95% CI: 1.11-1.86), whereas in AD non-users increased risk was seen in those from Nordic countries other than Sweden (IRR: 1.58; 95% CI: 1.08-2.29). Antidepressant users with higher education had an increased risk of non-fatal SH (IRR: 1.34; 95% CI: 1.12-1.61), in both men and women.

conclusionsForeign country of birth was associated with increased risk for non-fatal SH in older adults with and without AD therapies. Being married was a protective factor for non-fatal SH in men. The complex association between sociodemographic factors and use of antidepressants in the occurrence of self-harm in older men and women indicates the need for multifaceted tailored preventive strategies including healthcare and social services alike.

Indexed as

DepressionDepressive DisorderAgedAged, 80 and overAntidepressive AgentsCase-Control StudiesCohort StudiesEducational StatusEmigrants and ImmigrantsFemaleHumansIncidenceMaleMarital StatusPregnancyResearch DesignAntidepressive AgentsAntidepressantsCohort studyOlder adultsPharmacoepidemiologyRegistriesSelf-harmSociodemographic factors

Identifiers

PMID32539817
PMCPMC7296708
OpenAlexW3034254631

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.