Evidence map›Paper›PMID 32539714›Full record

ArticleBMC infectious diseases2020

The correlations between Th1 and Th2 cytokines in human alveolar echinococcosis.

Xiao Ma, Xuefei Zhang, Jia Liu, Yufang Liu, Cunzhe Zhao, Huixia Cai, Wen Lei, Junying Ma, Haining Fan, Jianye Zhou and 9 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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  5. Immunoprotective effect and mechanism of rEg.P29 against CD4Acta biochimica et biophysica Sinica · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Xiao MaQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Xuefei ZhangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Jia LiuQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Yufang LiuQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Cunzhe ZhaoQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Huixia CaiQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China. huixia_1107@163.com.
Wen LeiQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Junying MaQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Haining FanQinghai University Affiliated Hospital, Xining, 810000, Qinghai Province, China. fanhaining@medmail.com.cn.
Jianye ZhouBiomedical Research Center, Northwest Minzu University, Lanzhou, 730000, Gansu Province, China.
Na LiuQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Jingxiao ZhangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Yongshun WangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Wei WangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Peizhen ZhanQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Xiongying ZhangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Qing ZhangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Kemei ShiQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Peiyun LiuQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, Qinghai Province, China.
Qinghai Institute for Endemic Diease Prevention and Control · CNMinzu University of China · CNQinghai University Affiliated Hospital · CN

Funding

Science and Technology Major Project of Qinghai Province No. 2016-SF-A5
6 · The paper itself

Abstract

backgroundAlveolar echinococcosis (AE) is a zoonotic parasitic disease caused by Echinococcus multilocularis larval tapeworm infections in humans that severely impairs the health of affected patients in the northern hemisphere.

methodsThe expression levels of 20 cytokines associated with AE infection were measured by enzyme-linked immunosorbent assay, and the correlations between these cytokines were analysed in the R programming language.

resultsSerum cytokine levels differed among individuals in both the AE patient and healthy control groups. The results of the correlations among the cytokines showed obvious differences between the two groups. In the AE patients group, Th1 and Th2 cytokines formed a more complicated network than that in the healthy control group.

conclusionsThe altered correlations between Th1 and Th2 cytokines may be closely associated with AE infection, which may provide a new explanation for the essential differences between AE patients and healthy individuals.

Indexed as

Th1-Th2 BalanceAdultAnimalsCytokinesEchinococcosisEchinococcus multilocularisFemaleHumansMaleMiddle AgedCytokinesAlveolar echinococcosisCorrelation analysisEchinococcus multilocularisTh1 cytokinesTh2 cytokines

Identifiers

PMID32539714
PMCPMC7294603
OpenAlexW3095768669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.