ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2020
Olfactory and Oral Manifestations of COVID-19: Sex-Related Symptoms-A Potential Pathway to Early Diagnosis.
Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 12 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
88 citing papers in PubMed, 12 syntheses or guidelines pooled it, 232 citations in OpenAlex.
- The assessment of qualitative olfactory dysfunction in COVID-19 patients: a systematic review of tools and their content validity.Frontiers in psychology · 2023Pooled it
- Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis.Chemical senses · 2023Pooled it
- Prevalence of oral manifestations in COVID-19: A systematic review.Reviews in medical virology · 2022Pooled it
- Oral Health Implications of SARS-CoV-2/COVID-19: A Systematic Review.Oral health & preventive dentistry · 2022Pooled it
- The prevalence of olfactory and gustatory dysfunction in covid-19 - A systematic review.Auris, nasus, larynx · 2022Pooled it
- Pooled it
- What can the neurological manifestations of COVID-19 tell us: a meta-analysis.Journal of translational medicine · 2021Pooled it
- Prevalence of Olfactory Dysfunction in Coronavirus Disease 2019 (COVID-19): A Meta-analysis of 27,492 Patients.The Laryngoscope · 2021Pooled it
- Regional and Chronological Variation of Chemosensory Dysfunction in COVID-19: a Meta-Analysis.Journal of Korean medical science · 2021Pooled it
- Oral Manifestations of COVID-19: Updated Systematic Review With Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Frequency and Clinical Utility of Olfactory Dysfunction in COVID-19: a Systematic Review and Meta-analysis.Current allergy and asthma reports · 2020Pooled it
- Prevalence of Chemosensory Dysfunction in COVID-19 Patients: A Systematic Review and Meta-analysis Reveals Significant Ethnic Differences.ACS chemical neuroscience · 2020Pooled it
- The effect of artificial saliva on the control of dry mouth: a semi-experimental study on COVID-19 patients under Non-invasive mechanical ventilation.BMC oral health · 2024Trial
- Validity and reliability of the Hebrew version of the Brief Questionnaire of Olfactory Disorders (Brief-QOD) and the Self-Reported Mini Olfactory Questionnaire (Self-MOQ).Journal of patient-reported outcomes · 2025Article
- Oral health, smoking status, and oral manifestations of adult patients with SARS-CoV-2 during the Omicron outbreak in China: a cross-sectional study.Scientific reports · 2025Article
- Oral hygiene influence on the incidence and severity of oral manifestations in Coronavirus Disease 2019.BMC oral health · 2025Article
- Gender-based differences in telomere attrition and long-term respiratory dysfunction in COVID-19 ICU survivors one year post-infection: implications for aging-associated pulmonary decline.Frontiers in immunology · 2025Article
- Respiratory symptom patterns in healthcare workers in Germany: a prospective study during the SARS-CoV-2 pandemic.Frontiers in public health · 2025Observational
- Oral manifestations of COVID-19 vaccinated individuals, post-infection, and different variants: a Brazilian population study.Brazilian oral research · 2025Article
- Obliteration of oral and maxillofacial region by SARS-CoV-2 infection.GMS hygiene and infection control · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe coronavirus disease 2019 (COVID-19) pandemic poses a threat to global health. Early diagnosis is an essential key to limit the outbreak of the virus. STUDY
designCase series, study conducted between March 25, 2020, and April 15, 2020.
settingAmbulatory, nonhospitalized patients who were quarantined in a designated hotel for COVID-19 patients and were recruited by an advertisement at the hotel. SUBJECTS AND
methodsIn total, 140 patients participated in a web-based questionnaire assessing initial symptoms of common viral diseases, olfactory and taste functions, xerostomia, and orofacial pain.
resultsA total of 58 men and 70 women participated. Initial symptoms were cough (59.4%), weakness (47.7%), myalgia (46.9%), fever (42.2%), headache (40.6%), impaired sense of smell (38.3%), impaired sense of taste (32.8%), sore throat (26.6%), runny nose (26.6%), and nasal congestion (22.7%). All symptoms were more frequent among women; however, only runny nose was statistically significant (
conclusionA considerable number of patients presented with olfactory and oral disorders. Interestingly, women presented with a different cluster of symptoms than men, which may suggest a new clinical approach to diagnosing COVID-19 disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.