Evidence map›Paper›PMID 32539340›Full record

ArticleACS nano2020

DNA Tetrahedra Modules as Versatile Optical Sensing Platforms for Multiplexed Analysis of miRNAs, Endonucleases, and Aptamer-Ligand Complexes.

Zhixin Zhou, Yang Sung Sohn, Rachel Nechushtai, Itamar Willner

Abstract read
In one paragraph

Article in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  14. Trigger-activated autonomous DNA machine for amplified liver cancer biomarker microRNA21 imaging.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Article
  15. Recent Advances in DNA Nanomaterials.Nanomaterials (Basel, Switzerland) · 2023
    Review
  16. PhotocleavableChemical reviews · 2023
    Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhixin ZhouInstitute of Chemistry, The Minerva Center for Biohybrid Complex Systems, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0003-0450-1921
Yang Sung SohnInstitute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Rachel NechushtaiInstitute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Itamar WillnerInstitute of Chemistry, The Minerva Center for Biohybrid Complex Systems, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0001-9710-9077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sensing modules for analyzing miRNAs or the endonucleases consist of tetrahedra functionalized with three different fluorophore-quencher pairs in spatially quenched configurations and hairpin units acting as recognition elements for the analytes. Three different miRNAs (miRNA-21, miRNA-221, and miRNA-155) or three different endonucleases (Nt.BbvCI,

Indexed as

Aptamers, NucleotideBiosensing TechniquesMicroRNAsDNAEndonucleasesLigandsAptamers, NucleotideDNAEndonucleasesLigandsMicroRNAsDNA nanotechnologyfluorescencesensorsthrombinVEGF

Identifiers

PMID32539340
PMCPMC7467810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.