Evidence map›Paper›PMID 32539213›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2020

Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca

Bernard T Drumm, Benjamin E Rembetski, Kaitlin Huynh, Aqeel Nizar, Salah A Baker, Kenton M Sanders

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Orai storeoperated CaChannels (Austin, Tex.) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Pharmacologic treatments for gastroparesis.Pharmacological reviews · 2025
    Review
  9. Article
  10. Effect of propinox and pinaverium bromide onFrontiers in pharmacology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Interstitial cells of the sip syncytium regulate basal membrane potential in murine gastric corpus.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  16. CaPhysiological reviews · 2024
    Review
  17. Article
  18. Article
  19. The enteric nervous system.Physiological reviews · 2023
    Review
  20. A Study on the Effects of Muscarinic and Serotonergic Regulation byInternational journal of medical sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bernard T DrummDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Benjamin E RembetskiDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Kaitlin HuynhDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Aqeel NizarDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Salah A BakerDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Kenton M SandersDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
University of Nevada, Reno · USDundalk Institute of Technology · IE

Funding

Tissue, Cell and Tissue Culture CoreP01DK041315 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KEEF, KATHLEEN D · 1989 to 2018
$26.3M
Single Cell Molecular ExpressionP30GM110767 · NIGMS · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2014 to 2018
$5.4M
Role of interstitial cells of Cajal in patterned colonic motor activityR01DK120759 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Sal Baker, KENTON M SANDERS · 2019 to 2026
$3.4M
NIDDK NIH HHS P01 DK041315NIDDK NIH HHS R01 DK120759NIGMS NIH HHS P30 GM110767
6 · The paper itself

Abstract

Colonic intramuscular interstitial cells of Cajal (ICC-IM) are associated with cholinergic varicosities, suggesting a role in mediating excitatory neurotransmission. Ca

Indexed as

AnimalsAnoctamin-1CalciumCholinergic AgentsColonElectric StimulationInterstitial Cells of CajalMembrane PotentialsMiceMice, Inbred C57BLMuscle ContractionMuscle, SmoothReceptors, MuscarinicSynaptic TransmissionAnoctamin-1CalciumCholinergic AgentsReceptors, MuscarinicCa2+ imagingCa2+ storescholinergicc-Kitgastrointestinal motilityoptogeneticsSIP syncytium

Identifiers

PMID32539213
PMCPMC7790594
OpenAlexW3034571737

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.