Evidence map›Paper›PMID 32539207›Full record

ArticleCancer science2020

Investigating the health disparities in the association between lifestyle behaviors and the risk of head and neck cancer.

Jenn-Ren Hsiao, Cheng-Chih Huang, Chun-Yen Ou, Chan-Chi Chang, Wei-Ting Lee, Sen-Tien Tsai, Jehn-Shyun Huang, Ken-Chung Chen, Yu-Hsuan Lai, Yuan-Hua Wu and 9 more

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Jenn-Ren HsiaoDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Cheng-Chih HuangDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chun-Yen OuDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chan-Chi ChangDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wei-Ting LeeDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Sen-Tien TsaiDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Jehn-Shyun HuangDepartment of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ken-Chung ChenDepartment of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yu-Hsuan LaiInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yuan-Hua WuDepartment of Radiation Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wei-Ting HsuehDepartment of Radiation Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Shang-Yin WuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chia-Jui YenInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Jang-Yang ChangDivision of Hematology/Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen-Lin LinDepartment of Nursing, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ya-Ling WengNational Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Han-Chien YangNational Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Yu-Shan ChenDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Jeffrey S ChangNational Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.ORCID https://orcid.org/0000-0002-3236-6205
National Cheng Kung University Hospital · TWNational Health Research Institutes · TW

Funding

Health ResearchMinistry of Science and TechnologyMinistry of Science and Technology, Taiwan 107-2314-B-006-041-MY3National Health Research Institutes CA-109-PP-01
6 · The paper itself

Abstract

Many studies have reported a positive association between lower socioeconomic status (SES) and higher head and neck cancer (HNC) risk. Fewer studies have examined the impact of SES on the association between alcohol or cigarette use and HNC risk. The current case-control study (1104 HNC cases and 1363 controls) investigated the influence of education, a SES indicator, on the association between HNC and the use of alcohol, cigarettes, or betel quids in Taiwan, a country with universal health care. Our results showed a larger increase in HNC risk associated with alcohol among those with lower educational level (odds ratio [OR] = 2.07; 95% confidence interval [CI], 1.53-2.80) than those with higher educational level (OR = 1.38; 95% CI, 1.04-1.85) (heterogeneity-P = .03). Educational level had an influence on the association between alcohol use and HNC risk among those with genetic susceptibility (ALDH2-deficient) to the carcinogenic effect of alcohol. The association between cigarette or betel quid use and HNC risk was similar between the high and low educational groups. National policies and social interventions have led to the decline in the prevalence of cigarette and betel quid users in Taiwan. In contrast, due to the lack of adequate alcohol control policies, alcohol consumption in Taiwan has continued to rise. A higher impact of alcohol on HNC risk among lower SES individuals even with universal health care could be the result of insufficient alcohol control policies in Taiwan.

Indexed as

Health Status DisparitiesLife StyleAlcohol DrinkingAldehyde Dehydrogenase, MitochondrialCalcium CompoundsCase-Control StudiesEducational StatusFemaleGenetic Predisposition to DiseaseHead and Neck NeoplasmsHumansMaleMiddle AgedOxidesPiperPlant ExtractsAldehyde Dehydrogenase, MitochondrialALDH2 protein, humanCalcium Compoundslime-piper betel quidOxidesPlant Extractsalcoholcase-controlhead and neck cancerrisksocioeconomic status

Identifiers

PMID32539207
PMCPMC7419018
OpenAlexW3035650197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.