Evidence map›Paper›PMID 32538553›Full record

ArticleBrain and behavior2020

Effective connectivity during autobiographical memory search.

Norberto Eiji Nawa, Hiroshi Ando

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In one paragraph

Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Common and distinct correlates of construction and elaboration of episodic-autobiographical memory: An ALE meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Norberto Eiji NawaCenter for Information and Neural Networks (CiNet), National Institute of Information and Communications Technology (NICT), Osaka, Japan.ORCID 0000-0001-5969-0606
Hiroshi AndoCenter for Information and Neural Networks (CiNet), National Institute of Information and Communications Technology (NICT), Osaka, Japan.

Funding

Japan Society for the Promotion of Science JP17K00220
6 · The paper itself

Abstract

introductionWe used dynamic causal modeling (DCM) to examine effective connectivity during cued autobiographical memory (AM) search in a left-hemispheric network consisting of six major regions within the large network of brain regions recruited during memory retrieval processes.

methodsFunctional MRI data were acquired while participants were shown verbal cues describing common life events and requested to search for a personal memory associated with the cue. We examined directed couplings between the ventromedial (vmPFC), dorsomedial (dmPFC), and dorsolateral prefrontal cortices (dlPFC), hippocampus, angular gyrus, and the posterior midline cortex (RSC/PCC/Prec).

resultsDuring AM search, the vmPFC, dlPFC, and RSC/PCC/Prec acted as primary drivers of activity in the rest of the network. Moreover, when AM search completed successfully (Hits), the effective connectivity of the hippocampus on the vmPFC and angular gyrus was up-modulated. Likewise, there was an increase in the influence of the RSC/PCC/Prec in the activity of the dlPFC and dmPFC. Further analysis indicated that the modulation observed during Hits is primarily a distributed phenomenon that relies on the interplay between different brain regions.

conclusionThese results suggest that prefrontal and posterior midline cortical regions together with the dlPFC largely coordinate the processes underlying AM search, setting up the conditions on which the angular gyrus and the hippocampus may act upon when the outcome of the search is successful.

Indexed as

Memory, EpisodicAdultBrainBrain MappingCuesFemaleHumansMagnetic Resonance ImagingMaleMental RecallYoung Adultautobiographical memorydynamic causal modelingepisodic memoryhippocampusventromedial prefrontal cortex

Identifiers

PMID32538553
PMCPMC7428471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.