Evidence map›Paper›PMID 32538036›Full record

ArticleJournal of epidemiology and global health2020

Effectiveness of Oseltamivir Prophylaxis in Influenza Outbreaks in Residential Aged Care.

Mithilesh Dronavalli, Heidi Lord, Kate Alexander, Leng Boonwaat, Narugopal Pal, Stephanie Mahalia Fletcher-Lartey

Abstract read
In one paragraph

Article in Journal of epidemiology and global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Modeling the Impacts of Antiviral Prophylaxis Strategies in Mitigating Seasonal Influenza Outbreaks in Nursing Homes.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mithilesh DronavalliPublic Health Unit, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.
Heidi LordCentre for Research in Nursing and Health, St George Hospital, South Eastern Sydney Local Health District, Australia.
Kate AlexanderPublic Health Unit, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.
Leng BoonwaatPublic Health Unit, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.
Narugopal PalPublic Health Unit, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.
Stephanie Mahalia Fletcher-LarteyPublic Health Unit, South Western Sydney Local Health District, Liverpool, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza outbreaks in Aged Care Facilities (ACFs) can lead to hospitalizations and deaths. Influenza can spread rapidly through ACFs if precautionary measures are not taken. Along with influenza vaccination and precautionary hygiene measures, Oseltamivir Prophylaxis (OP) may be effective in reducing the attack rate of influenza by preventing new cases. A cohort study was carried out to investigate the effectiveness of OP use during influenza outbreaks in ACFs located within South Western Sydney Local Health District from 1 January 2015 to 31 December 2018. The main outcome assessed was the rate of OP failure (new cases of influenza in patients treated with OP) among ACF residents. Subgroups and various predictors of OP failure were investigated including presence of a dementia ward, high care ward, and days to Public Health Unit (PHU) notification. The cohort consisted of 86 ACF outbreaks involving 10,064 residents. OP prevented 90% of influenza cases during influenza outbreaks [0.1 RR (95% confidence interval (CI): 0.08-0.12);

Indexed as

Antiviral AgentsDisease OutbreaksHomes for the AgedInfluenza, HumanOseltamivirPost-Exposure ProphylaxisAgedCohort StudiesHumansNew South WalesTreatment OutcomeAntiviral AgentsOseltamiviraged care facilitiesInfluenzaoseltamiviroutbreaksprophylaxispublic health preparednessvaccination

Identifiers

PMID32538036
PMCPMC7310780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.