Evidence map›Paper›PMID 32537948›Full record

ArticleMolecular genetics & genomic medicine2020

Haplotypic diversity and population genetic study of a population in Kashi region by 27 Y-chromosomal short tandem repeat loci.

Yaoshun Liu, Xiaoyue Jin, Yuxi Guo, Xingrui Zhang, Wu Zhu, Wenli Zhang, Ting Mei

RetractedAbstract readRetracted Publication
In one paragraph

Article in Molecular genetics & genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yaoshun LiuAnkang Hospital of Traditional Chinese Medicine, Ankang, China.
Xiaoyue JinAnkang Hospital of Traditional Chinese Medicine, Ankang, China.
Yuxi GuoAnkang Hospital of Traditional Chinese Medicine, Ankang, China.
Xingrui ZhangAnkang Hospital of Traditional Chinese Medicine, Ankang, China.
Wu ZhuAnkang Hospital of Traditional Chinese Medicine, Ankang, China.
Wenli ZhangDepartment of Clinical Laboratory, Children's Hospital, Urumqi, China.
Ting MeiDepartment of Clinical Laboratory, Children's Hospital, Urumqi, China.ORCID 0000-0003-1900-6552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundY-chromosomal short tandem repeats (Y-STRs) have been certified to be the serviceable markers for some paternity cases in the last few years.

methodsWe presented the gene diversity, haplotypic diversity, and forensic statistical parameters of 340 unrelated Uighur males from Kashi region based on the 27 Y-STRs. Genomic DNA was extracted from bloodstain samples using the Chelex-100 method and amplified by Yfiler

resultsGene diversity values on the 27 Y-STRs ranged from 0.4749 (at DYS437 locus) to 0.9416 (at DYS385a,b loci). According to forensic parameters of the 27 Y-STR loci, 295 disparate haplotypes were acquired, 258 of which were unique. The haplotypic diversities and discrimination capacities at Yfiler plus 27 loci, Yfiler 17 loci, extended 11 loci, and minimal 9 loci were 0.9990 and 0.8676; 0.9961 and 0.6912; 0.9952 and 0.5941; and 0.9919 and 0.5676, respectively. Multidimensional scaling plot and neighbor-joining tree between the studied Uighur group and 17 reference populations were conducted, and the obtained results indicated the Kashi Uighur group had the closer genetic relationships with Uighur groups living in different regions.

conclusionTo sum up, the present study may provide valuable population data and background information of Kashi Uighur group.

Indexed as

Microsatellite RepeatsPolymorphism, GeneticChinaChromosomes, Human, YEthnicityHaplotypesHumansMaleforensic geneticsgenetic relationshiphaplotypic diversityKashi Uighur ethnic groupY-STR

Identifiers

PMID32537948
PMCPMC7434754

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