ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2020
Evaluation of a simple image-based tool to quantify facial erythema in rosacea during treatment.
Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
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- A Prospective Randomized Controlled Pilot Study to Assess the Response and Tolerability of Cold Atmospheric Plasma for Rosacea.Skin pharmacology and physiology · 2023Trial
- Clinical characteristics and treatment of Morbihan disease of the eyelids: A single-center retrospective study.Indian journal of ophthalmology · 2026Article
- Quantifying Erythema and Skin Tone Variation in Cutaneous Rashes: A Colorimetric Approach.Cureus · 2026Article
- Calcium Hydroxylapatite-Carboxymethylcellulose as a Treatment for Forearm Dermatoporosis: A Prospective, Delayed-Start, Contralateral Case Series.Journal of cosmetic dermatology · 2026Article
- The Kesty Redness Scale: A Pilot Validation Study for a Novel Tool for Evaluating Facial Redness in Cosmetic and Clinical Dermatology.Journal of cosmetic dermatology · 2025Article
- Microneedle radiofrequency for skin rejuvenation: bridging image-derived metrics and photographic assessment.Frontiers in medicine · 2025Article
- Analysis of blood untargeted metabolomic characteristics of different subtypes of rosacea.Frontiers in molecular biosciences · 2025Article
- Objectively quantifying facial erythema in rosacea aided by the ImageJ analysis of VISIA red images.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Article
- Skin color classification of Koreans using clustering.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022Article
- Evaluation of Erythema Severity in Dermatoscopic Images of Canine Skin: Erythema Index Assessment and Image Sampling Reliability.Sensors (Basel, Switzerland) · 2021Article
- Evaluation of a simple image-based tool to quantify facial erythema in rosacea during treatment.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2020Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFacial erythema is a common symptom in rosacea. To overcome subjectivity in scoring erythema severity, objective redness quantification is desirable. This study evaluated an image-based erythema quantification tool to monitor facial erythema in rosacea patients during treatment and compared these values to clinical scores. MATERIALS AND
methodsTwenty-one rosacea patients were treated with topical ivermectin for 16 weeks. Clinical erythema scores and clinical photographs were taken at week 0, 6, 16 and 28. Using ImageJ, RGB images were split into red, green and blue channels to measure the green/red ratio of lesional skin compared with a green sticker. With CIELAB colour space, a* (indicating colour from green to red) of a lesional and non-lesional facial site was measured, calculating ∆a*. Interobserver concordance and correlation between quantitative and clinical erythema values were determined.
resultsTreatment resulted in reduction of clinical erythema scores. No significant changes in red/green ratios were measured. Lesional a* and ∆a* significantly decreased from baseline to week 16 and 28 (P < .05). A weak correlation existed between clinical scores and lesional a* (R
conclusionImageJ is a simple, rapid, objective and reproducible tool to monitor erythema in rosacea patients during treatment. The photographs allow retrospective analysis, evaluation of large and small lesions, and discrimination of subtle redness differences. We recommend using lesional a* to monitor erythema of inflammatory dermatoses in clinical practice.
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