Evidence map›Paper›PMID 32537774›Full record

ArticleThe Journal of physiology2020

Effect of acute nitrite infusion on contractile economy and metabolism in isolated skeletal muscle in situ during hypoxia.

Simone Porcelli, Letizia Rasica, Brian S Ferguson, Andreas N Kavazis, James McDonald, Michael C Hogan, Bruno Grassi, L Bruce Gladden

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Simone PorcelliInstitute of Biomedical Technologies, National Research Council, Segrate, Italy.ORCID 0000-0002-9494-0858
Letizia RasicaInstitute of Biomedical Technologies, National Research Council, Segrate, Italy.ORCID 0000-0001-6943-9845
Brian S FergusonMyoKardia, San Francisco, CA, USA.
Andreas N KavazisSchool of Kinesiology, Auburn University, Auburn, AL, USA.
James McDonaldSchool of Kinesiology, Auburn University, Auburn, AL, USA.ORCID 0000-0002-4738-369X
Michael C HoganDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-3877-7088
Bruno GrassiDepartment of Medicine, University of Udine, Udine, Italy.ORCID 0000-0003-3188-1659
L Bruce GladdenSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Auburn University · USMyriad Genetics · USUniversity of California San Diego · USUniversity of Milan · ITUniversity of Pavia · ITUniversity of Udine · IT

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
Assessing and Alleviating Skeletal Muscle Ca2+ Handling Dysfunction in SarcopeniaR01AR069577 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOGAN, MICHAEL C · 2017 to 2021
$1.7M
NCATS NIH HHS KL2 TR000450NCATS NIH HHS KL2 TR002346NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIAMS NIH HHS AR-06 9577NIAMS NIH HHS R01 AR069577
6 · The paper itself

Abstract

key pointsIncreased plasma nitrite concentrations may have beneficial effects on skeletal muscle function. The physiological basis explaining these observations has not been clearly defined and it may involve positive effects on muscle contraction force, microvascular O ABSTRACT: Contrasting findings have been reported concerning the effects of augmented nitric oxide (NO) on skeletal muscle force production and oxygen consumption (

Indexed as

Muscle ContractionOxygenAnimalsDogsHypoxiaMuscle, SkeletalOxygen ConsumptionOxygenmitochondrial respirationnitric oxidenitrite infusionoxidative metabolism

Identifiers

PMID32537774
PMCPMC7434220
OpenAlexW3034186414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.