Evidence map›Paper›PMID 32537729›Full record

ArticleEuropean radiology2020

The vestibular aqueduct ossification on temporal bone CT: an old sign revisited to rule out the presence of endolymphatic hydrops in Menière's disease patients.

Jeanne Mainnemarre, Charlotte Hautefort, Michel Toupet, Jean-Pierre Guichard, Emmanuel Houdart, Arnaud Attyé, Michael Eliezer

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In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  5. Dual-target corticosteroid therapy for refractory Ménière's disease: influence of vestibular aqueduct patency and endotypes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  14. Cross-sectional Area of the Superior Petrosal Sinus is Reduced in Patients with Significant Endolymphatic Hydrops.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jeanne MainnemarreNeuroradiology Unit, Department of Neuroradiology, Lariboisière University Hospital, 75010, Paris, France.
Charlotte HautefortDepartment of Head and Neck Surgery, Lariboisière University Hospital, Paris, France.
Michel ToupetCentre d'Explorations Fonctionnelles Otoneurologiques, Paris, France.
Jean-Pierre GuichardNeuroradiology Unit, Department of Neuroradiology, Lariboisière University Hospital, 75010, Paris, France.
Emmanuel HoudartNeuroradiology Unit, Department of Neuroradiology, Lariboisière University Hospital, 75010, Paris, France.
Arnaud AttyéNeuroradiology Unit, Department of Neuroradiology, Lariboisière University Hospital, 75010, Paris, France.
Michael EliezerNeuroradiology Unit, Department of Neuroradiology, Lariboisière University Hospital, 75010, Paris, France. michael.eliezer@aphp.fr.ORCID http://orcid.org/0000-0002-4973-1790
Hôpital Lariboisière · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMenière's disease (MD) is associated with endolymphatic hydrops (EH), which is an accumulation of excessive endolymphatic fluid in the inner ear. However, using temporal bone CT, lower visualization rates of the vestibular aqueduct (VA) in these patients have also been reported.

methodsIn this retrospective single-center imaging study, we have included 25 healthy subjects and 47 patients having a definite, probable, or possible clinical diagnosis of MD that underwent temporal bone CT and inner ear MRI performed 4 h after contrast media administration. Two radiologists independently ranked the morphology of the VA in healthy subjects and in MD patients, using a three-level score (completely visible, discontinuous, and not visible). Each subject was then graded, based on both the VA's appearance and on EH presence.

resultsIn healthy subjects, the VA was normal (grade 0) in 22/25 (88%) ears and discontinuous (grade I) in 3 healthy ears (12%). In the symptomatic ears of MD patients, we found 17/56 ears (30.3%) with VA grade 0, 15/56 ears (26.8%) with grade I, and 24/56 ears (42.8%) with grade II (p < 0.001). In MD patients, EH was observed in 46/94 ears (48.9%). A VA of grade 0 would eliminate the presence of EH with a negative predictive value of 88.6%, while a VA grade II would predict the presence of saccular hydrops with a positive predictive value of 93.1%.

conclusionThe evaluation by temporal bone CT of the VA can predict the presence of EH on MRI with a high positive predictive value. KEY POINTS: • The evaluation by temporal bone CT of the vestibular aqueduct can predict the presence of EH on MRI. • A vestibular aqueduct of grade 0 would eliminate the presence of EH on MRI with a negative predictive value of 88.6%. • A vestibular aqueduct grade II would predict the presence of endolymphatic hydrops on MRI with a positive predictive value of 93.1%.

Indexed as

OsteogenesisAdultAgedAudiometryCase-Control StudiesContrast MediaEar, InnerEdemaEndolymphatic HydropsFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMeniere DiseaseMiddle AgedContrast MediaEndolymphatic hydrops (EH)Inner earMagnetic resonance imaging (MRI)Menière’s diseaseVestibular aqueduct

Identifiers

PMID32537729
OpenAlexW3034645270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.