ArticleDiabetologia2020
Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study.
Article in Diabetologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- The Outcomes of Sodium-Glucose Co-transporter 2 Inhibitors (SGLT2I) on Diabetes-Associated Neuropathy: A Systematic Review and meta-Analysis.Frontiers in pharmacology · 2022Pooled it
- A Systematic Review of Lifestyle Interventions for Neuropathy and Neuropathic Pain: Alcohol Consumption and Avoidance.Brain sciences · 2026Review
- Risk Factors of Sural Nerve Axonal Degeneration Using Clinically Relevant Thresholds in Context of Glucose Metabolism: The Maastricht Study.Muscle & nerve · 2026Article
- Article
- Prevalence of Peripheral Neuropathy Among Very Old Adults: Evidence From the Michigan Neuropathy Screening Instrument.Journal of the American Geriatrics Society · 2025Article
- A Systematic Review of Lifestyle Interventions for Neuropathy and Neuropathic Pain: Smoking Cessation.NeuroSci · 2025Review
- Combined Associations of Type 2 Diabetes and Peripheral Neuropathy With Device-Measured Physical Activity and Sedentary Behaviour-The Maastricht Study.Diabetes/metabolism research and reviews · 2025Article
- Changes Over 10 Years in Peripheral Nerve Function in People With Well-Controlled Type 2 Diabetes and Those With Normal Glucose Tolerance.Neurology · 2025Observational
- Common Peroneal Nerve Paralysis Following Rapid Weight Loss-A Case Report and Literature Review.Nutrients · 2025Review
- Glucagon: a potential protective factor against peripheral nerve compromise in patients with type 2 diabetes and obesity.Diabetology & metabolic syndrome · 2025Article
- Nerve conduction velocity studies in diabetic peripheral neuropathy involving sural nerve-A meta-analysis.Journal of family medicine and primary care · 2024Article
- Peripheral neuropathy in patients with gout, beyond focal nerve compression: a cross-sectional study.Clinical rheumatology · 2024Article
- Painful Diabetic Neuropathy: The Need for New Approaches.Journal of diabetes science and technology · 2024Review
- Observational
- New perspectives in diabetic neuropathy.Neuron · 2023Review
- Study on risk factors of diabetic peripheral neuropathy and establishment of a prediction model by machine learning.BMC medical informatics and decision making · 2023Article
- Evidence of impaired H-reflex and H-reflex rate-dependent depression in diabetes, prediabetes and obesity: a mini-review.Frontiers in endocrinology · 2023Review
- Article
- (Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study.Scientific reports · 2022Article
- Towards prevention of diabetic peripheral neuropathy: clinical presentation, pathogenesis, and new treatments.The Lancet. Neurology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisWe aimed to examine associations of cardiometabolic risk factors, and (pre)diabetes, with (sensorimotor) peripheral nerve function.
methodsIn 2401 adults (aged 40-75 years) we previously determined fasting glucose, HbA
resultsHyperglycaemia (fasting glucose or HbA CONCLUSIONS/
interpretationHyperglycaemia (including the non-diabetic range) was most consistently associated with early-stage nerve damage. Nonetheless, larger waist circumference, inflammation, history of hypertension and smoking may also independently contribute to worse nerve function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.