Evidence map›Paper›PMID 32536942›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2020

Mitochondrial activity disruption and local muscle damage induced in mice by

Judith Tabullo De Robles, Francisca Fernández Valverde, Lucero Valladares Cisneros, Juana Hernández Villeda, Ayixon Sánchez-Reyes, María Del Carmen Gutiérrez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Judith Tabullo De RoblesCenter of Biotechnology Research, Autonomous University of the State of Morelos (UAEM), Cuernavaca, Mexico.
Francisca Fernández ValverdeManuel Velasco Suárez National Institute of Neurology and Neurosurgery, México City, Mexico.
Lucero Valladares CisnerosCenter of Biotechnology Research, Autonomous University of the State of Morelos (UAEM), Cuernavaca, Mexico.
Juana Hernández VilledaManuel Velasco Suárez National Institute of Neurology and Neurosurgery, México City, Mexico.
Ayixon Sánchez-ReyesCátedras Conacyt-Institute of Biotechnology, National Autonomous University of Mexico (UNAM), Cuernavaca, Mexico.
María Del Carmen GutiérrezCenter of Biotechnology Research, Autonomous University of the State of Morelos (UAEM), Cuernavaca, Mexico.ORCID 0000-0002-1439-1386
Universidad Autónoma del Estado de Morelos · MXInstituto Nacional de Neurología y Neurocirugía · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsVenom was collected and fractionated using RP-HPLC; mouse

resultsCK activity was higher in EDL muscle exposed to venom than in unexposed muscle. This increase was observed after 15 min of venom incubation, and remained stable up to 45 min. Venom-exposed EDL muscle showed signs of muscle damage including necrosis, loss of fascicular structure as well as mitochondrial accumulations and ragged red fibers (RRF), suggesting an impairment in the normal mitochondrial arrangement. Nicotinamide adenine dinucleotide (NADH) and cytochrome oxidase (COX) tests also indicate that respiratory complexes might be affected.

conclusionOur results suggest a different biochemical composition of

Indexed as

CentipedeMyotoxic activityVenom

Identifiers

PMID32536942
PMCPMC7269145
OpenAlexW3033846678

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.