Evidence map›Paper›PMID 32536864›Full record

ArticleFrontiers in pharmacology2020

SNHG1 Inhibits ox-LDL-Induced Inflammatory Response and Apoptosis of HUVECs

Yuan Lu, Jue Xi, Yao Zhang, Wensu Chen, Fengyun Zhang, Chenzong Li, Zhirong Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuan LuDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Jue XiDepartment of Endocrinology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yao ZhangDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Wensu ChenDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Fengyun ZhangDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Chenzong LiDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Zhirong WangDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction of human endothelial cells is an important trigger for atherosclerosis. Oxidative low-density lipoprotein (ox-LDL) usually was used to stimulate the dysfunction of human umbilical vein endothelial cells (HUVECs). LncRNA SNHG1 (small nucleolar RNA host gene 1) is a cerebral infarction-associated gene. The present study was designed to investigate the role of SNHG1 in ox-LDL-induced HUVECs. Cell viability was evaluated by CCK-8 and MTT assay. Cell apoptosis was detected by flow cytometry analysis. Cell inflammatory response was evaluated by detecting LDH, IL-6, IL-1

Indexed as

atherosclerosisG protein subunit alpha i2miR-556-5ppoly(rC) binding protein 1small nucleolar RNA host gene 1

Identifiers

PMID32536864
PMCPMC7266976
OpenAlexW3032017841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.