Evidence map›Paper›PMID 32536603›Full record

ArticleMolecular & cellular proteomics : MCP2020

Ionizing Radiation-induced Proteomic Oxidation in

Steven T Bruckbauer, Benjamin B Minkoff, Deyang Yu, Vincent L Cryns, Michael M Cox, Michael R Sussman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. SynonymousNAR genomics and bioinformatics · 2024
    Article
  4. Article
  5. Thiol Reductases inAntioxidants (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Radiation-InactivatedVaccines · 2021
    Article
  10. Article
  11. Physiology of Highly RadioresistantFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Steven T BruckbauerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Benjamin B MinkoffCenter for Genomic Science Innovation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Deyang YuDepartment of Medicine, University of Wisconsin Carbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Wisconsin, USA.
Vincent L CrynsDepartment of Medicine, University of Wisconsin Carbone Cancer Center, School of Medicine and Public Health, University of Wisconsin-Madison, Wisconsin, USA.
Michael M CoxDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA. Electronic address: msussman@wisc.edu.
Michael R SussmanDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA; Center for Genomic Science Innovation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA. Electronic address: cox@biochem.wisc.edu.
University of Wisconsin–Madison · US

Funding

BACTERIAL PROTEINS INVOLVED IN DNA REPAIRR01GM052725 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COX, MICHAEL M. · 1996 to 2007
$1.7M
Molecular basis of ionizing radiation resistanceR01GM112757 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COX, MICHAEL M. · 2017 to 2020
$1.2M
Numerical Investigation of Collective Cell MigrationSC2GM112575 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI ZENG, XIAOWEI · 2015 to 2017
$441k
NIGMS NIH HHS R01 GM052725NIGMS NIH HHS R01 GM112757NIGMS NIH HHS SC2 GM112575
6 · The paper itself

Abstract

Recent work has begun to investigate the role of protein damage in cell death because of ionizing radiation (IR) exposure, but none have been performed on a proteome-wide basis, nor have they utilized MS (MS) to determine chemical identity of the amino acid side chain alteration. Here, we use

Indexed as

ProteomicsRadiation, IonizingAmino AcidsAmino Acid SequenceCatalytic DomainDeinococcusEscherichia coliHydroxylationMolecular WeightOxidation-ReductionPeptidesProteolysisProteomeAmino AcidsPeptidesProteomebacteriaglyceraldehyde-3-phosphate dehydrogenaseionizing radiationomicsoxidative stressprotein oxidationproteomequantificationTandem mass spectrometry

Identifiers

PMID32536603
PMCPMC8015010
OpenAlexW3034920684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.