Evidence map›Paper›PMID 32536273›Full record

ArticleHypertension (Dallas, Tex. : 1979)2020

Mid- to Late-Life Time-Averaged Cumulative Blood Pressure and Late-Life Cardiac Structure, Function, and Heart Failure.

Kanako Teramoto, Wilson Nadruz Junior, Kunihiro Matsushita, Brian Claggett, Jenine E John, Hicham Skali, Scott Solomon, Susan Cheng, Amil M Shah

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Observational
  9. Impact of barometric pressure on blood pressure during dialysis: Introducing intradialytic time-averaged cumulative systolic blood pressure (TACsBP-inD) as a new metric.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025
    Article
  10. Article
  11. Association of Cumulative Systolic Blood Pressure With Left Atrial Function in the Setting of Normal Left Atrial Size: The Atherosclerosis Risk in Communities (ARIC) Study.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2024
    Article
  12. Article
  13. Associations between long-term averages of metabolic parameters in adulthood and cardiac structure and function in later life.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. Blood pressure in heart failure management and prevention.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

  • Commented on by
    2021
5 · Who and what money

Authors and funding

9 authors.

Kanako TeramotoFrom the Division of Cardiology, St Marianna University School of Medicine Hospital, Kanagawa, Japan (K.T.).
Wilson Nadruz JuniorCardiology Division, State University of Campinas, São Paulo, Brazil (W.N.J.).
Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD (K.M.).
Brian ClaggettDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (K.T., B.C., J.E.J., H.S., S.S., A.M.S.).
Jenine E JohnDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (K.T., B.C., J.E.J., H.S., S.S., A.M.S.).
Hicham SkaliDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (K.T., B.C., J.E.J., H.S., S.S., A.M.S.).
Scott SolomonDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (K.T., B.C., J.E.J., H.S., S.S., A.M.S.).
Susan ChengSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (S.C.).
Amil M ShahDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (K.T., B.C., J.E.J., H.S., S.S., A.M.S.).

Funding

Mapping the Progression to HFpEF in the Elderly through Longitudinal Changes in Cardiac FunctionR01HL135008 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Amil M Shah · 2017 to 2026
$11.5M
The Microvascular Aging and Eicosanoids - Women's Evaluation of Systemic Aging Tenacity (MAE-WEST) ("You are never too old to become younger!") Specialized Center for Research Excellence (SCORE)U54AG065141 · NIA · CEDARS-SINAI MEDICAL CENTER · PI SHYY, JOHN YJ · 2020 to 2024
$8.7M
Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8M
Cardiac microstructure and the immune-inflammatory response to SARS-CoV-2R01HL131532 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHENG, SUSAN, LI, DEBIAO · 2016 to 2025
$6.6M
Early Detection of Transthyretin Cardiac Amyloidosis: Defining a Novel Target for HFpEF Treatment and Prevention in Late LifeR01HL150342 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA, SHAH, AMIL M · 2020 to 2023
$4.1M
Quantifying cardiac structure and function to define the progression to hear failure in African AmericansR01HL143224 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAH, AMIL M · 2018 to 2021
$3.4M
Mediators of Systemic Inflammation and Heart Failure Risk in the CommunityR01HL143227 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHENG, SUSAN · 2019 to 2022
$3.3M
Ventricular-vascular coupling in the elderly: lifecourse determinants, trajectories, and prognostic significanceR01HL142983 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHENG, SUSAN, MITCHELL, GARY FRANK · 2019 to 2022
$3.2M
Mentoring patient-oriented research in deep phenotyping of cardiac function for heart failure preventionK24HL152008 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAH, AMIL M · 2020 to 2024
$608k
NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS K24 HL152008NHLBI NIH HHS R01 HL131532NHLBI NIH HHS R01 HL135008NHLBI NIH HHS R01 HL142983NHLBI NIH HHS R01 HL143224NHLBI NIH HHS R01 HL143227NHLBI NIH HHS R01 HL150342NHLBI NIH HHS T32 HL094301NIA NIH HHS U54 AG065141
6 · The paper itself

Abstract

Limited data exist regarding systolic blood pressure (SBP) through mid- to late-life and late-life cardiac function and heart failure (HF) risk. Among 4578 HF-free participants in the ARIC study (Atherosclerosis Risk in Communities) attending the fifth visit (2011-2013; age 75±5 years), time-averaged cumulative SBP was calculated as the sum of averaged SBPs from adjacent consecutive visits (visits 1-5) indexed to total observation time (24±1 years). Calculations were performed using measured SBPs and also incorporating antihypertensive medication specific effect constants (underlying SBP). Outcomes included comprehensive echocardiography at visit 5 and post-visit 5 incident HF, HF with preserved ejection fraction, and reduced ejection fraction. Higher cumulative SBP was associated with greater left ventricular mass and worse diastolic measures (all

Indexed as

EchocardiographyHeart FailureHeart VentriclesHypertensionAgedBlood PressureEarly Medical InterventionFemaleHeart Disease Risk FactorsHumansJapanMaleOrgan SizePrognosisPublic HealthStroke Volumeblood pressureechocardiographyheart failure

Identifiers

PMID32536273
PMCPMC8262121

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.