SynthesisJournal of nephrology2020
Donor-transmitted cancer in kidney transplant recipients: a systematic review.
Synthesis in Journal of nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Donor-Transmitted Cancer in Orthotopic Solid Organ Transplant Recipients: A Systematic Review.Transplant international : official journal of the European Society for Organ TransplantationPooled it
- Skin cancer detection and organ donation.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Article
- Urologic malignancy in renal transplant recipients: Analysis of OPTN/UNOS data from 2000 to 2022.BMC cancer · 2026Article
- Onco-nephrology in kidney transplant recipients: challenges and evolving strategies.Frontiers in immunology · 2026Review
- Donor-transmitted squamous cell carcinoma in kidney transplant recipient successfully treated with checkpoint inhibitors: a case report.Frontiers in oncology · 2026Article
- Utilization and outcomes of lung transplant from donors with cancer: a UNOS study.Journal of thoracic disease · 2025Article
- A retrospective single-center pilot study of the genetic background of the transplanted kidney.PloS one · 2025Article
- Donors With Previous Malignancy: When Is It Safe to Proceed With Organ Transplantation?Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- Endocrine malignancies: a still neglected issue in kidney transplantation.Frontiers in medicine · 2025Review
- [Fluorescence confocal microscopy-complete digitization of pathology].Pathologie (Heidelberg, Germany) · 2024Article
- Cross-individual cancer transmission to children during the gestational and perinatal periods.Cancer science · 2024Review
- Effectiveness and safety of immunosuppressive regimens used as maintenance therapy in kidney transplantation: The CESIT study.PloS one · 2024Observational
- The value of organ and tissue biovigilance: a cross-sectional analysis.Frontiers in transplantation · 2024Article
- Chapter 1: Evaluation of kidney function in patients undergoing anticancer drug therapy, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy 2022.International journal of clinical oncology · 2023Review
- Second Opinion in the Italian Organ Procurement Transplantation: The Pathologist Is In.Clinics and practice · 2023Article
- Transmission of pancreatic adenocarcinoma by a single multiorgan donor to two kidney transplant recipients: A case report.Frontiers in medicine · 2023Article
- Donors With a Prior History of Cancer: Factors of Non-Utilization of Kidneys for Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Association between Immunosuppressive Therapy Utilized in the Treatment of Autoimmune Disease or Transplant and Cancer Progression.Biomedicines · 2022Review
- Tolvaptan ameliorated kidney function for one elderly autosomal dominant polycystic kidney disease patient: A case report.World journal of clinical cases · 2022Article
- Immune checkpoint inhibitors for solid organ transplant recipients: clinical updates.Korean journal of transplantation · 2022Review
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transmission of cancer from a donor organ is a rare event but has important consequences. Aim of this systematic review was to summarize all the published evidence on cancer transmission in kidney recipients. We reviewed published case reports and series describing the outcome of recipients with donor-transmitted cancer until August 2019. A total of 128 papers were included, representing 234 recipients. The most common transmitted cancers were lymphoma (n = 48, 20.5%), renal cancer (42, 17.9%), melanoma (40, 17.1%), non-small cell lung cancer (n = 13, 5.6%), neuroendocrine cancers comprising small cell lung cancer (n = 11, 4.7%) and choriocarcinoma (n = 10, 4.3%). There was a relative lack of glioblastoma and gastrointestinal cancers with only 6 and 5 cases, respectively. Melanoma and lung cancer had the worst prognosis, with 5-years overall survival of 43% and 19%, respectively; while renal cell cancer and lymphomas had a favorable prognosis with 5-years overall survival of 93 and 63%, respectively. Metastasis of cancer outside the graft was the most important adverse prognostic factor. Overall reporting was good, but information on donors' cause of death and investigations at procurement was often lacking. Epidemiology of transmitted cancer has evolved, thanks to screening with imaging and blood tests, as choriocarcinoma transmission have almost abolished, while melanoma and lymphoma are still difficult to detect and prevent.
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