Evidence map›Paper›PMID 32535744›Full record

ArticleCell biology and toxicology2021

TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways.

Yujing Wang, Hang Li, Chu Xue, Hao Chen, Yanning Xue, Fang Zhao, Michael X Zhu, Zhengyu Cao

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biology and toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  9. Activation of transient receptor potential vanilloid 3 is required for keratinocyte differentiation and epidermal barrier formation.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Article
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  17. International journal of molecular sciences · 2024
    Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yujing Wang *State Key Laboratory of Natural Medicines and Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Development, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.ORCID https://orcid.org/0000-0003-2197-8983
Hang Li *State Key Laboratory of Natural Medicines and Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Development, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.ORCID https://orcid.org/0000-0002-0750-8355
Chu XueState Key Laboratory of Natural Medicines and Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Development, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.ORCID https://orcid.org/0000-0003-2700-6800
Hao ChenInstitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, 210042, Jiangsu, China.ORCID https://orcid.org/0000-0003-0857-7405
Yanning XueJiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.ORCID https://orcid.org/0000-0001-6677-260X
Fang ZhaoState Key Laboratory of Natural Medicines and Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Development, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China. 1620184499@cpu.edu.cn.ORCID https://orcid.org/0000-0002-5774-2238
Michael X ZhuDepartment of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.ORCID https://orcid.org/0000-0002-5676-841X
Zhengyu CaoState Key Laboratory of Natural Medicines and Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Development, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China. zycao1999@hotmail.com.ORCID https://orcid.org/0000-0002-2692-2949
China Pharmaceutical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNNanjing University of Chinese Medicine · CNThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient receptor potential vanilloid 3 (TRPV3) is highly expressed in skin keratinocytes where it forms Ca

Indexed as

Signal TransductionAdministration, TopicalAnimalsCalciumCell ProliferationChromonesCymenesEpidermisErbB ReceptorsHaCaT CellsHEK293 CellsHumansHyperplasiaKeratinocytesMiceMice, Inbred C57BL2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneCalciumcarvacrolChromonesCymenesErbB ReceptorsMorpholinesPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsTransforming Growth Factor alphaTRPV3 protein, humanTrpv3 protein, mouseTRPV Cation ChannelsEGFRKeratinocytesProliferationTRPV3

Identifiers

PMID32535744
OpenAlexW3035630848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.