Evidence map›Paper›PMID 32535738›Full record

ArticleEuropean radiology2020

MR imaging of epithelial ovarian cancer: a combined model to predict histologic subtypes.

LuoDan Qian, JiaLiang Ren, AiShi Liu, Yang Gao, FenE Hao, Lei Zhao, Hui Wu, GuangMing Niu

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In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
  2. Integrated Radiomics-Enhanced machine learning models for accurate diagnosis and prediction of oGVHD-Related ocular complications.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  8. Artificial Intelligence in Obstetric and Gynecological MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

LuoDan QianDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.
JiaLiang RenGE Healthcare (Shanghai) Co., Ltd., Shanghai, 210000, China.
AiShi LiuDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.
Yang GaoDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.
FenE HaoDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.
Lei ZhaoDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.
Hui WuDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China. terrywuhui@sina.com.
GuangMing NiuDepartment of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China. Cjr.niuguangming@vip.163.com.ORCID http://orcid.org/0000-0001-5915-0837

Funding

Natural Science Foundation of Inner Mongolia 2017MS(LH)0837
6 · The paper itself

Abstract

objectiveTo compare the performance of clinical features, conventional MR image features, ADC value, T2WI, DWI, DCE-MRI radiomics, and a combined multiple features model in predicting the type of epithelial ovarian cancer (EOC).

methodsIn this retrospective analysis, 61 EOC patients were confirmed by histology. Significant features (p < 0.05) by multivariate logistic regression were retained to establish a clinical model, conventional MRI morphological model, ADC model, and traditional model. The radiomics model included FS-T2WI, DWI, and DCE-MRI, and also, a multisequence model was established. A total of 1070 radiomics features of each sequence were extracted; then, univariate analysis and LASSO were used to select important features. Traditional models were combined with a combined radiomics model to establish a mixed model. The predictive performance was validated by receiver operating characteristic curve (ROC) analysis, calibration curve, and decision curve analysis (DCA). A stratified analysis was conducted to compare the differences between the combined radiomics model and the traditional model in identifying early- and late-stage EOC.

resultsTraditional models showed the highest performance (AUC = 0.96). The performance of the mixed model (AUC = 0.97) was not significantly different from that of the traditional model. The calibration curve showed that the traditional model had the highest reliability. Stratified analysis showed the potential of the combined radiomics model in the early distinction of the two tumor types.

conclusionThe traditional model is an effective tool to distinguish EOC type I/II. Combined radiomics models have the potential to better distinguish EOC types in early FIGO stage disease. KEY POINTS: • The combined radiomics model resulted in a better predictive model than that from a single sequence model. • The traditional model showed higher classification accuracy than the combined radiomics model. • Combined radiomics models have the potential to better distinguish EOC types in early FIGO stage disease.

Indexed as

Neoplasm StagingAdultAgedAged, 80 and overCarcinoma, Ovarian EpithelialFemaleHumansMagnetic Resonance ImagingMiddle AgedOvarian NeoplasmsPrognosisReproducibility of ResultsRetrospective StudiesROC CurveEpithelial ovarian cancerHistopathologyMagnetic resonance imagingRadiomics

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.