Observational studyObesity research & clinical practice
Obesity prolongs the hospital stay in patients affected by COVID-19, and may impact on SARS-COV-2 shedding.
Observational study in Obesity research & clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 5 of them syntheses that pooled it.
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Who cites it
68 citing papers in PubMed, 5 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- Global prevalence and effect of comorbidities and smoking status on severity and mortality of COVID-19 in association with age and gender: a systematic review, meta-analysis and meta-regression.Scientific reports · 2023Pooled it
- The negative impact of obesity on the occurrence and prognosis of the 2019 novel coronavirus (COVID-19) disease: a systematic review and meta-analysis.Eating and weight disorders : EWD · 2022Pooled it
- A systematic review and meta-analysis of obesity and COVID-19 outcomes.Scientific reports · 2021Pooled it
- A meta-analysis of the association between obesity and COVID-19.Epidemiology and infection · 2020Pooled it
- COVID-19 infection and body weight: A deleterious liaison in a J-curve relationship.Obesity research & clinical practicePooled it
- Host proteins associated with strong neutralizing SARS-CoV-2 antibody responses in a South African cohort.Communications medicine · 2026Article
- Impact of metabolically healthy and metabolically unhealthy obesity on cardiac arrest and mortality in pulmonary embolism hospitalizations in elderly patients with cancer.Lung India : official organ of Indian Chest Society · 2026Article
- COVID-19 induces persistent transcriptional changes in adipose tissue that are not associated with Long COVID.bioRxiv : the preprint server for biology · 2025Article
- Factors Associated with Prolonged SARS-CoV-2 Viral Positivity in an Italian Cohort of Hospitalized Patients.Diseases (Basel, Switzerland) · 2024Article
- Article
- SARS-CoV-2 Infection Alters the Phenotype and Gene Expression of Adipocytes.International journal of molecular sciences · 2024Article
- Clinical characteristics of COVID-19 in children: a large multicenter study from Iran.Frontiers in pediatrics · 2024Article
- Time to recovery and its determinant factors among patients with COVID-19 in Assosa COVID-19 treatment center, Western Ethiopia.Pneumonia (Nathan Qld.) · 2023Article
- Sex Differences among Overweight/Obese Kidney Transplant Recipients Requiring Oxygen Support Amid the COVID-19 Pandemic.Medicina (Kaunas, Lithuania) · 2023Article
- Effect of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV.JCI insight · 2023 · on this mapArticle
- Ct,Future science OA · 2023Article
- OBESITY AND OUTCOME AMONG PATIENTS HOSPITALIZED FOR SARS-COV-2: A HOSPITAL-BASED STUDY IN INDONESIA.African journal of infectious diseases · 2023Article
- Vitamin C as a Potential Interplaying Factor between Obesity and COVID-19 Outcome.Healthcare (Basel, Switzerland) · 2022Article
- Body Mass Index and Clinical Outcomes in Adult COVID-19 Patients of Diverse Ethnicities.Healthcare (Basel, Switzerland) · 2022Article
- SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages.Science translational medicine · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOn the last three months the new SARS-COV-2 coronavirus has created a pandemic, rapidly spreading all around the world. The aim of the study is to investigate whether obesity impacts on COVID-19 morbidity.
methodsOne hundred consecutive patients with COVID-19 pneumonia admitted in our Medical Unit were evaluated. Anthropometric parameters and past medical history were registered. Nasopharyngeal swab samples and biochemical analysis were obtained at admission and during hospital stay.
resultsPatients with (OB, 29) and without obesity (N-OB, 71) were similar in age, gender and comorbidities, with the exception of hypertension that was more frequent in OB group. At admission, inflammatory markers were higher in OB than N-OB group. OB group showed a worse pulmonary clinical picture, with lower PaO2 (57 ± 15 vs. 68 ± 14 mmHg, p = 0.042), and SaO2 (88 ± 6 vs. 92 ± 5%, p = 0.049) at admission consequently requiring higher volumes of oxygen (Fi02: 38 ± 15 vs. 29 ± 19%, p = 0.047) and a longer period to achieve oxygen weaning (10 ± 6 vs. 15 ± 7 days, p = 0.03). OB group also had positive swabs for longer time (19 ± 8 vs. 13 ± 7, days, p = 0.002), and required longer hospital stay (21 ± 8 vs. 13 ± 8, days, p = 0.0008). Partial least square regression analysis showed that BMI, age and CRP at admission were related to longer length of hospital stay, and time for negative swab. On the contrary, in this cohort, obesity did not predict higher mortality.
conclusionsSubjects with obesity affected by COVID-19 require longer hospitalization, more intensive and longer oxygen treatment, and they may have longer SARS-COV-2 shedding.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.