Observational studyCardiovascular diabetology2020
Type 2 diabetes mellitus increases the mortality risk after acute coronary syndrome treated with coronary artery bypass surgery.
Observational study in Cardiovascular diabetology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Impacts of metabolic disorders on short- and long-term mortality after coronary artery surgery in the elderly.BMC cardiovascular disorders · 2022Trial
- Preoperative Systemic Immune-Inflammation Index as an Independent Predictor of Postoperative Wound Infection in Diabetic CABG Patients.Journal of cardiovascular development and disease · 2026Article
- Efficacy of Empagliflozin Versus Placebo in Patients With Recent Acute Myocardial Infarction: A Systematic Review.Cureus · 2025Review
- Article
- A Narrative Review of Diabetic Macroangiopathy: From Molecular Mechanism to Therapeutic Approaches.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Review
- The association between SGLT2 inhibitors and new-onset acute coronary syndrome in the elderly: a population-based longitudinal cohort study.Diabetology & metabolic syndrome · 2023Article
- Using preoperative N-terminal pro-B-type natriuretic peptide levels for predicting major adverse cardiovascular events and myocardial injury after noncardiac surgery in Chinese advanced-age patients.Journal of geriatric cardiology : JGC · 2022Article
- Machine learning algorithms for predicting mortality after coronary artery bypass grafting.Frontiers in cardiovascular medicine · 2022Article
- Predictors of Rehospitalization and Mortality in Diabetes-Related Hospital Admissions.Journal of clinical medicine · 2021Article
- Diabetic heart disease: A clinical update.World journal of diabetes · 2021Review
- Treatment strategies in patients with diabetes and three-vessel coronary disease: What should we choose?Cardiovascular diabetology · 2021Article
- Real-world outcomes of different treatment strategies in patients with diabetes and three-vessel coronary disease: a mean follow-up 6.3 years study from China.Cardiovascular diabetology · 2021Observational
- Effect of glycaemic control on coronary artery bypass grafting outcomes - a United Kingdom centre experience.JRSM cardiovascular diseaseArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType 2 diabetes mellitus (DM) is a risk factor for cardiovascular diseases and is common among patients undergoing coronary artery bypass grafting (CABG) surgery. The main objective of our study was to investigate the impact of DM type 2, and its treatment subgroups, on short- and long-term mortality in patients with acute coronary syndrome (ACS) who undergo CABG.
methodsThe study included 1307 patients enrolled from the biennial Acute Coronary Syndrome Israeli Survey between 2000 and 2016, who were hospitalized for ACS and underwent CABG. Of them, 527 (40%) patients were with and 780 (60%) were without DM.
resultsCompared with the non-diabetic group, the diabetic group of patients comprised more women and had more comorbidities such as hypertension, dyslipidemia, renal impairment, peripheral vascular disease and prior ischemic heart disease. Overall 30-day mortality rate was similar between DM and non-DM patients (4.2% vs. 4%, p = 0.976). Ten-year mortality rate was higher in DM compared with non-diabetic patients (26.6% vs. 17.7%, log-rank p < 0.001), and higher in the subgroup of insulin-treated patients compared to non-insulin treated patients (31.5% vs. 25.6%, log-rank p = 0.019). Multivariable analysis showed that DM increased the mortality hazard by 1.61-fold, and insulin treatment among the diabetic patients increased the mortality hazard by 1.57-fold.
conclusionsWhile type 2 DM did not influence the in-hospital mortality hazard, we showed that the presence of DM among patients with ACS referred to CABG, is a powerful risk factor for long-term mortality, especially when insulin was included in the diabetic treatment strategy.
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