Evidence map›Paper›PMID 32533826›Full record

ArticleIntegrative and comparative biology2020

Grand Challenges in Comparative Tooth Biology.

C Darrin Hulsey, Karly E Cohen, Zerina Johanson, Nidal Karagic, Axel Meyer, Craig T Miller, Alexa Sadier, Adam P Summers, Gareth J Fraser

Abstract read
In one paragraph

Article in Integrative and comparative biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Loss, persistence and reversal of phenotypic traits.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  2. Article
  3. Article
  4. Teeth outside the jaw: Evolution and development of the toothed head clasper in chimaeras.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Integrative organismal biology (Oxford, England) · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C Darrin HulseyDepartment of Biology, University of Konstanz, Konstanz, 78464, Germany.
Karly E CohenFriday Harbor Laboratories, School of Aquatic and Fishery Sciences, Department of Biology, University of Washington, WA 98195, USA.
Zerina JohansonDepartment of Earth Sciences, Natural History Museum, London SW7 5HD, UK.
Nidal KaragicDepartment of Biology, University of Konstanz, Konstanz, 78464, Germany.
Axel MeyerDepartment of Biology, University of Konstanz, Konstanz, 78464, Germany.
Craig T MillerDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA 94720, USA.
Alexa SadierDepartment of Ecology and Evolution, University of California Los Angeles, Los Angeles, CA 90032, USA.
Adam P SummersFriday Harbor Laboratories, School of Aquatic and Fishery Sciences, Department of Biology, University of Washington, WA 98195, USA.
Gareth J FraserDepartment of Biology, University of Florida, Gainesville, FL 32611, USA.

Funding

Development Genetics of Tooth Number Variation in SticklebacksR01DE021475 · NIDCR · UNIVERSITY OF CALIFORNIA BERKELEY · PI MILLER, CRAIG THOMAS · 2011 to 2025
$5.4M
NIDCR NIH HHS R01 DE021475
6 · The paper itself

Abstract

Teeth are a model system for integrating developmental genomics, functional morphology, and evolution. We are at the cusp of being able to address many open issues in comparative tooth biology and we outline several of these newly tractable and exciting research directions. Like never before, technological advances and methodological approaches are allowing us to investigate the developmental machinery of vertebrates and discover both conserved and excitingly novel mechanisms of diversification. Additionally, studies of the great diversity of soft tissues, replacement teeth, and non-trophic functions of teeth are providing new insights into dental diversity. Finally, we highlight several emerging model groups of organisms that are at the forefront of increasing our appreciation of the mechanisms underlying tooth diversification.

Indexed as

Biological EvolutionToothVertebratesAnimals

Identifiers

PMID32533826
PMCPMC7821850

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.