Evidence map›Paper›PMID 32533356›Full record

SynthesisSurgical endoscopy2020

Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis: a systemic review and meta-analysis.

Yan Lin, Yan Su, Jun Yan, Xun Li

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Gallstones and common bile duct stones management: Single-stageWorld journal of gastrointestinal endoscopy · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  9. Rendezvous procedure for choledocholithiasis in a Canadian rural surgical service.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan LinThe First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.
Yan SuThe First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Jun YanThe Second Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Xun LiThe First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China. lxdr21@126.com.ORCID 0000-0003-2005-7322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ideal management for patients with cholecystocholedocholithiasis is still controversial. Laparoendoscopic rendezvous (LERV), combined with laparoscopy and endoscopy, is a novel and attractive technique. The aim of this research was to compare LERV with traditional two-stage management, preoperative ERCP and laparoscopic cholecystectomy (ERCP + LC), for treating patients with cholecystocholedocholithiasis.

methodFour databases, the Cochrane Library, PubMed, Embase, and Medline, all updated to through September 2019, were searched to identify comparative studies on LERV versus ERCP + LC for treating cholecystocholedocholithiasis. Total operative time, successful common bile duct (CBD) stone clearance, postoperative morbidity, conversion to other procedures, and length of hospital stay were evaluated. Pooled data were measured by odds ratios (ORs) and mean difference (MD) with 95% confidence intervals (CIs).

resultsEight studies with a total of 1061 patients were included in this meta-analysis, including 542 patients who received LERV and 519 patients who received ERCP + LC. There was no significant difference between the two groups regarding successful CBD stone clearance (OR 2.20, P = 0.10), postoperative bleeding (OR 0.67, P = 0.37), postoperative cholangitis (OR 0.66, P = 0.53), postoperative bile leak (OR 0.87, P = 0.81), or conversion to other procedures (OR 0.75, P = 0.62). The total operative time was longer in the LERV group (MD = 44.93, P < 0.00001), while LERV was associated with less postoperative pancreatitis than the two-stage management group (OR 0.26, P = 0.0003). The incidence of overall morbidity was lower in the LERV group than in the two-stage management group (OR 0.41, P < 0.0001), and the LERV group had a shorter hospital stay (MD = - 3.52, P < 0.00001).

conclusionLERV is equivalent to traditional two-stage procedures in terms of CBD stone clearance and conversion, with less pancreatitis, lower overall morbidity, and shorter hospital stay but longer operation time. More clinical trials are needed to determine the best treatment for patients in different conditions.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholecystectomy, LaparoscopicCholangitisCholedocholithiasisFemaleGallstonesHumansIncidenceLength of StayMaleMiddle AgedOdds RatioOperative TimePancreatitisPostoperative ComplicationsCholecystocholedocholithiasisEndoscopic retrograde cholangiopancreatographyLaparoendoscopic rendezvousLaparoscopic cholecystectomy

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.