ReviewBiological trace element research2021
Micronutrients Profile in Oral Lichen Planus: a Review Literature.
Review in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Association of vitamin D levels and oral lichen planus. Systematic review and meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2024Pooled it
- Systematic Review and Meta-Analysis of Oxidative Stress and Antioxidant Markers in Oral Lichen Planus.Oxidative medicine and cellular longevity · 2021Pooled it
- Supplementary zinc and vitamin D in management of symptomatic oral lichen planus: a three-arm randomized clinical trial.BMC oral health · 2025Trial
- Association of Sleep Quality, Nutritional Factors, and Salivary Melatonin and Cortisol Levels with Oral Lichen Planus: A Case-Control Study.Biomedicines · 2026Article
- Association Between Oral Lichen Planus and Non-Oral Cancers: A Multicentre Case-Control SIPMO Study.Oral diseases · 2026Article
- Relationship Between Anemia and Oral Lichen Planus: New Therapeutic Perspectives Based on Anemia Management-A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Comparative Study of the Expressions of Nuclear (∆EX3) and Cytoplasmic (2B) Survivins in Oral Squamous Cell Carcinoma and Oral Lichen Planus Using Real-Time PCR.Clinical and experimental dental research · 2025Article
- Role of micronutrition in patients with oral cancer and nutritional intervention strategies.Frontiers in nutrition · 2025Review
- Associations of single and multiple vitamin levels with pediatric oral mucosal diseases: a cross-sectional study with multi-model analysis.Frontiers in nutrition · 2025Article
- Role of Vitamin D in Oral Lichen Planus: A Case Control Study.Nutrients · 2024Article
- Animal models to study the pathogenesis and novel therapeutics of oral lichen planus.Frontiers in oral health · 2024Article
- What can we learn from treatments of oral lichen planus?Frontiers in cellular and infection microbiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral lichen planus (OLP) is a relatively common chronic inflammatory disease. The micronutrients are critical factors in health of oral mucous and proper function of immune system. There have not been any review articles for evaluating trace element levels before and after standard treatments of OLP. The purpose of this study is to provide complete review of the association of micronutrients with OLP. Databases including PubMed, Google Scholar, Scopus, and Embase (Ovid) with keywords of oral lichen planus, OLP, oral disorder, micronutrients, trace element, nutrient element, antioxidant, oxidative stress, malnutrition, and essential trace elements, without time limitation (1900-2019) were searched to collect data on related articles. Total number of 58 original articles including 12 randomized clinical trials, 41 case-control, 4 case reports, and 1 cell line research were reviewed in this study. Lower levels of iron and its associated markers, such as hemoglobin and ferritin, increased levels of TIBC; reduced levels of zinc, calcium, vitamin D, vitamin B12, folic acid, and antioxidants such as vitamins C and E; and increased levels of oxidants and homocysteine, have been reported in OLP patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.