Evidence map›Paper›PMID 32533072›Full record

ArticleThe Journal of antibiotics2020

Antibacterial and cytotoxic metabolites of termite-associated Streptomyces sp. BYF63.

Le Zhang, Tao Song, Jun Wu, Shuxiang Zhang, Caiping Yin, Fang Huang, Yang Hang, Naeem Abbas, Xinhua Liu, Yinglao Zhang

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Frontiers in microbiology · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Polyene-ProducingFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Le ZhangSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Tao SongSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Jun WuSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Shuxiang ZhangSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Caiping YinSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Fang HuangSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Yang HangBiotechnology Center of Anhui Agricultural University, Anhui Agricultural University, 130 West Changjiang Rd, Hefei, 230036, Anhui, China.
Naeem AbbasSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China.
Xinhua LiuSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei, 230032, Anhui, China.
Yinglao ZhangSchool of Life Science, Anhui Agricultural University, 130 West Changjiang Rd., Hefei, 230036, Anhui, China. zhangyl@ahau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four anthraquinone derivatives, termstrin A, B, C and D (1-4), were isolated and purified from termite-associated Streptomyces sp. BYF63. Their structures were elucidated on the basis of extensive spectroscopic analyses (HR-ESI-MS, 1D and 2D NMR). Compounds 1 and 4 were found to possess potent antibacterial activities against Staphylococcus aureus, with the zone of inhibition (ZOI) values of 12.85 and 11.17 mm, respectively, which were comparable to that of penicillin sodium with ZOI of 13.15 mm. Furthermore, metabolite 1 showed moderate cytotoxicities against melanoma cell line A375 and gastric cancer cell line MGC-803, with IC

Indexed as

AnimalsAnthraquinonesAnti-Bacterial AgentsCell Line, TumorCytotoxinsHumansIsopteraMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusStreptomycesAnthraquinonesAnti-Bacterial AgentsCytotoxins

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.