Evidence map›Paper›PMID 32532984›Full record

ArticleNature communications2020

Adipocyte G

Lei Wang, Sai P Pydi, Lu Zhu, Luiz F Barella, Yinghong Cui, Oksana Gavrilova, Kendra K Bence, Cecile Vernochet, Jürgen Wess

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Activation of GScience advances · 2026
    Article
  2. Article
  3. Short-chain fatty acids.Nature metabolism · 2026
    Review
  4. Altered GScience advances · 2026
    Article
  5. Article
  6. Review
  7. Glucose sensing and homeostasis by adipocyte GPCR.Frontiers in endocrinology · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Cerebrovascular GMolecular imaging and biology · 2023
    Article
  17. Article
  18. Review
  19. Adipocyte GNature communications · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lei WangMolecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA.
Sai P PydiMolecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA.
Lu ZhuMolecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0003-2716-4649
Luiz F BarellaMolecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0003-2211-3842
Yinghong CuiMolecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA.
Oksana GavrilovaMouse Metabolism Core, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA.
Kendra K BenceInternal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer Inc, Cambridge, MA, 02139, USA.ORCID http://orcid.org/0000-0002-5879-4726
Cecile VernochetInternal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer Inc, Cambridge, MA, 02139, USA.
Jürgen WessMolecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 20892, USA. jurgenw@niddk.nih.gov.ORCID http://orcid.org/0000-0003-0818-1232
National Institute of Diabetes and Digestive and Kidney Diseases · USPfizer (United States) · US

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Metabolic Studies of Mouse Models of Obesity and DiabetesZICDK070002 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI GAVRILOVA, OKSANA · 2009 to 2025
$15.0M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Molecular basis of G protein-coupled receptor functionZIADK031129 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WESS, JURGEN · 2009 to 2025
$6.7M
NIDDK NIH HHS P30 DK020593NIDDK NIH HHS U24 DK059637
6 · The paper itself

Abstract

Adipocyte dysfunction links obesity to insulin resistance and type 2 diabetes. Adipocyte function is regulated by receptor-mediated activation of heterotrimeric G proteins. Little is known about the potential in vivo metabolic roles of G

Indexed as

AdipocytesAnimalsBlood GlucoseDiabetes Mellitus, Type 2Gene Expression ProfilingGlucose IntoleranceGTP-Binding Protein alpha Subunits, Gi-GoHomeostasisInsulinInsulin ResistanceMaleMice, Inbred C57BLMice, KnockoutMice, TransgenicObesitySignal TransductionBlood GlucoseGTP-Binding Protein alpha Subunits, Gi-GoInsulin

Identifiers

PMID32532984
PMCPMC7293267
OpenAlexW3035007251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.