ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
Early Visual Motion Experience Improves Retinal Encoding of Motion Directions.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Experience influences the refinement of feature selectivity in the mouse primary visual thalamus.Neuron · 2025Article
- Development and organization of the retinal orientation selectivity map.Nature communications · 2024Article
- Roles of visually evoked and spontaneous activity in the development of retinal direction selectivity maps.Trends in neurosciences · 2022Review
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Authors and funding
3 authors.
Funding
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Abstract
Altered sensory experience in early life often leads to altered response properties of the sensory neurons. This process is mostly thought to happen in the brain, not in the sensory organs. We show that in the mouse retina of both sexes, exposed to a motion-dominated visual environment from eye-opening, the ON-OFF direction selective ganglion cells (ooDSGCs) develop significantly stronger direction encoding ability for motion in all directions. This improvement occurs independent of the motion direction used for training. We demonstrated that this enhanced ability to encode motion direction is mainly attributed to increased response reliability of ooDSGCs. Closer examination revealed that the excitatory inputs from the ON bipolar pathway showed enhanced response reliability after the motion experience training, while other synaptic inputs remain relatively unchanged. Our results demonstrate that retina adapts to the visual environment during neonatal development.
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Registered trials
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