Evidence map›Paper›PMID 32532866›Full record

ArticleThe Journal of experimental biology2020

Evolutionarily conserved transcription factors drive the oxidative stress response in

Sarah M Ryan, Kaitie Wildman, Briseida Oceguera-Perez, Scott Barbee, Nathan T Mortimer, Alysia D Vrailas-Mortimer

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sarah M RyanUniversity of Denver, Department of Biological Sciences, Denver, CO 80210, USA.ORCID 0000-0002-9397-0449
Kaitie WildmanIllinois State University, School of Biological Sciences, Normal, IL 61790-4120, USA.
Briseida Oceguera-PerezIllinois State University, School of Biological Sciences, Normal, IL 61790-4120, USA.
Scott BarbeeUniversity of Denver, Department of Biological Sciences, Denver, CO 80210, USA.
Nathan T MortimerIllinois State University, School of Biological Sciences, Normal, IL 61790-4120, USA admorti@ilstu.edu ntmorti@ilstu.edu.ORCID 0000-0003-3787-9445
Alysia D Vrailas-MortimerUniversity of Denver, Department of Biological Sciences, Denver, CO 80210, USA admorti@ilstu.edu ntmorti@ilstu.edu.ORCID 0000-0001-5927-096X
Illinois State University · USUniversity of Denver · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
The Role of p38K and protein homeostasis in Limb-Girdle Muscular DystrophiesR15AR070505 · NIAMS · ILLINOIS STATE UNIVERSITY · PI VRAILAS-MORTIMER, ALYSIA DANIELLE · 2016 to 2016
$435k
NIAMS NIH HHS R15 AR070505NIH HHS P40 OD018537
6 · The paper itself

Abstract

As organisms are constantly exposed to the damaging effects of oxidative stress through both environmental exposure and internal metabolic processes, they have evolved a variety of mechanisms to cope with this stress. One such mechanism is the highly conserved p38 MAPK (p38K) pathway, which is known to be post-translationally activated in response to oxidative stress, resulting in the activation of downstream antioxidant targets. However, little is known about the role of p38K transcriptional regulation in response to oxidative stress. Therefore, we analyzed the p38K gene family across the genus

Indexed as

DrosophilaDrosophila ProteinsOxidative StressTranscription FactorsAnimalsDrosophila melanogasterp38 Mitogen-Activated Protein KinasesDrosophila Proteinslola protein, Drosophilap38 Mitogen-Activated Protein KinasesTranscription FactorsComparative genomicsGene regulationp38 MAPK

Identifiers

PMID32532866
PMCPMC7391405
OpenAlexW3034804708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.