Evidence map›Paper›PMID 32532832›Full record

ArticleScience immunology2020

Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma.

Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J Schmiedel, Shu Liang, Bjoern Peters, Alessandro Sette, Pandurangan Vijayanand

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 1 synthesis or guideline pooled it, 199 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Article
  7. Review
  8. Article
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  15. Asthma endotypes and theratypes.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  16. Antigen-specific TScience advances · 2026
    Article
  17. Article
  18. Review
  19. Review
  20. RecombinantFrontiers in immunology · 2026
    Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Grégory SeumoisLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. vijay@lji.org gregory@lji.org.ORCID 0000-0002-8164-6852
Ciro Ramírez-SuásteguiLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.ORCID 0000-0001-8126-710X
Benjamin J SchmiedelLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.ORCID 0000-0002-9103-9378
Shu LiangLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
Bjoern PetersLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.ORCID 0000-0002-8457-6693
Alessandro SetteLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.ORCID 0000-0001-7013-2250
Pandurangan VijayanandLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. vijay@lji.org gregory@lji.org.ORCID 0000-0001-7067-9723
La Jolla Institute for Immunology · US

Funding

Epigenomics of T cells and innate immune cells in human asthmaR01HL114093 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI ARSHAD, SYED HASAN, PETERS, BJOERN · 2011 to 2020
$8.5M
Understanding mechanisms in specific immunotherapy (SIT)U19AI100275 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SETTE, ALESSANDRO · 2012 to 2017
$8.1M
Towards the identification of biomarkers for pediatric milk allergyU19AI135731 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SETTE, ALESSANDRO · 2018 to 2022
$5.6M
Illumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NCRR NIH HHS S10 RR027366NHLBI NIH HHS R01 HL114093NIAID NIH HHS U19 AI100275NIAID NIH HHS U19 AI135731
6 · The paper itself

Abstract

CD4

Indexed as

Single-Cell AnalysisTranscriptomeAllergensAsthmaHumansHypersensitivityT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryAllergens

Identifiers

PMID32532832
PMCPMC7372639
OpenAlexW3034511947

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.