Evidence map›Paper›PMID 32532816›Full record

ArticleThe Journal of biological chemistry2020

The RNA-binding protein Hfq assembles into foci-like structures in nitrogen starved

Josh McQuail, Amy Switzer, Lynn Burchell, Sivaramesh Wigneshweraraj

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Chemical reviews · 2026
    Review
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  8. Review
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  12. Molecular biology of the cell · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. bioRxiv : the preprint server for biology · 2023
    Article
  17. Enhancing the antibacterial function of probioticApplied and environmental microbiology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Josh McQuailMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Amy SwitzerMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Lynn BurchellMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Sivaramesh WigneshwerarajMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom s.r.wig@imperial.ac.uk.ORCID 0000-0002-1418-4029
Imperial College London · GB

Funding

Medical Research Council MR/P028225/1Wellcome TrustWellcome Trust 100958
6 · The paper itself

Abstract

The initial adaptive responses to nutrient depletion in bacteria often occur at the level of gene expression. Hfq is an RNA-binding protein present in diverse bacterial lineages that contributes to many different aspects of RNA metabolism during gene expression. Using photoactivated localization microscopy and single-molecule tracking, we demonstrate that Hfq forms a distinct and reversible focus-like structure in

Indexed as

Adaptation, PhysiologicalGene Expression Regulation, BacterialEscherichia coliEscherichia coli ProteinsHost Factor 1 ProteinMultiprotein ComplexesNitrogenEscherichia coli ProteinsHfq protein, E coliHost Factor 1 ProteinMultiprotein ComplexesNitrogenbacteriophageenvironmental adaptationEscherichia coli (E. coli)gene expressiongene regulationHfq proteinnitrogen starvationphotoactivatable localization microscopy (PALM)RNA chaperonesmall regulatory RNA (sRNA)stress responseT7 phage

Identifiers

PMID32532816
PMCPMC7458820
OpenAlexW3034680017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.