Evidence map›Paper›PMID 32532691›Full record

GuidelineTransfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis2020

Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19.

Patrizia Accorsi, Pierluigi Berti, Vincenzo de Angelis, Giustina De Silvestro, Luca Mascaretti, Angelo Ostuni, Italian Society for Transfusion Medicine Immunohaematology (SIMTI) Italian Society for Hemapheresis cell Manipulation (SIdEM)

Open access · bronzeAbstract readPractice GuidelineReview
In one paragraph

Guideline in Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. COVID 19 convalescent plasma: Is there still a place for CCP?Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2023
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. The Convalescent Plasma Craze! Where Does India Stand?Journal of laboratory physicians · 2021
    Review
  8. A Perspective on COVID-19 Management.Journal of clinical medicine · 2021
    Review
  9. Safety and Efficacy of Convalescent Plasma in Elderly COVID-19 Patients: The RESCUE Trial.Mayo Clinic proceedings. Innovations, quality & outcomes · 2021
    Article
  10. Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Patrizia AccorsiDepartment of Haematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy.
Pierluigi BertiImmunohaematology and Transfusion Medicine, "Umberto Parini" Hospital, Aosta, Italy.
Vincenzo de AngelisTransfusion Medicine Department, Azienda Sanitaria Universitaria "Friuli Centrale", Udine, Italy. Electronic address: vincenzo.deangelis@asufc.sanita.fvg.it.
Giustina De SilvestroBlood Transfusion Service, University Hospital of Padua, Padua, Italy.
Luca MascarettiTransfusion Medicine Department, Azienda Sanitaria Universitaria "Giuliano Isontina", Trieste, Italy.
Angelo OstuniTransfusional Medicine Unit, University-Hospital Policlinico, Bari, Italy.
Italian Society for Transfusion Medicine Immunohaematology (SIMTI) Italian Society for Hemapheresis cell Manipulation (SIdEM)
Azienda Sanitaria Universitaria Integrata di Trieste · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Passive immunotherapy with plasma derived from patients convalescent from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that Blood Establishments are prepared to satisfy requests for immune plasma by defining the requirements applicable to plasma donors and the standards for preparation, qualification, storage, distribution and control of use of the product. This position paper is aimed to give recommendations on biological characteristics of a plasma preparation from convalescent donors and to support the evaluation of this therapeutic approach in more rigorous investigations.

Indexed as

Immunization, PassiveAntibodies, ViralBetacoronavirusBlood Component RemovalBlood DonorsCoronavirus InfectionsCOVID-19COVID-19 SerotherapyDonor SelectionHumansImmune SeraPandemicsPneumonia, ViralProduct LabelingRiskSARS-CoV-2Antibodies, ViralImmune SeraCOVID-19Immune plasma

Identifiers

PMID32532691
PMCPMC7239775
OpenAlexW3027102422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.