Evidence map›Paper›PMID 32532363›Full record

ReviewOncology research2020

CD13: A Key Player in Multidrug Resistance in Cancer Chemotherapy.

Qie Guo, Xiao Li, Meng-Na Cui, Jia-Lin Sun, Hong-Yan Ji, Bei-Bei Ni, Mei-Xing Yan

Abstract readReview
In one paragraph

Review in Oncology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Clinical features of immature leukemias in children.International journal of hematology · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Peptide-Based Drug Delivery Systems.Medicina (Kaunas, Lithuania) · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qie GuoDepartment of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China.
Xiao LiDepartment of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China.
Meng-Na CuiDepartment of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China.
Jia-Lin SunDepartment of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China.
Hong-Yan JiDepartment of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China.
Bei-Bei NiDepartment of Clinical Pharmacy, The Affiliated Hospital of Qingdao UniversityQingdao, ShandongP.R. China.
Mei-Xing YanDepartment of Pharmacy, Qingdao Women and Childrens HospitalQingdao, ShandongP.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the most serious diseases that are harmful to human health. Systemic chemotherapy is an optimal therapeutic strategy for the treatment of cancer, but great difficulty has been encountered in its administration in the form of multidrug resistance (MDR). As an enzyme on the outer cell surface, CD13 is documented to be involved in the MDR development of tumor cells. In this review, we will focus on the role of CD13 in MDR generation based on the current evidence.

Indexed as

Drug Resistance, MultipleDrug Resistance, NeoplasmApoptosisATP-Binding Cassette, Sub-Family C ProteinsCD13 AntigensHumansNeoplasmsNeoplastic Stem CellsOxidative StressReactive Oxygen SpeciesATP-Binding Cassette, Sub-Family C ProteinsCD13 AntigensReactive Oxygen Species

Identifiers

PMID32532363
PMCPMC7751223

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.