Observational studyCardiovascular ultrasound2020
Prognostic implications of tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure ratio in septic shock patients.
Observational study in Cardiovascular ultrasound, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06887140 (Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Value of Right Ventricular-pulmonary Arterial Coupling Assessed by Echocardiography in Septic Patients: A Prospective Observational Study
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Beyond APACHE II: the role of TAPSE in predicting mortality among septic patients and septic shock; a systematic review and metanalysis Right heart, right prognosis: TAPSE, a new tool for predicting mortality among septic patients and septic shock; a systematic review and metanalysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Pooled it
- Right ventricle to pulmonary artery coupling as a prognostic factor in tricuspid regurgitation: A systematic review.ESC heart failure · 2025Pooled it
- Left ventricular longitudinal function and the hyperkinetic profile: an old echo world to rediscover?Critical care (London, England) · 2026Article
- Noninvasive assessment of right ventricular-pulmonary artery coupling may predict acute kidney injury after primary PCI in STEMI patients.BMC cardiovascular disorders · 2026Article
- Article
- The prognostic role of tricuspid annular plane systolic excursion in critically ill patients with septic shock.Journal of anesthesia, analgesia and critical care · 2025Article
- Systolic Pulmonary Artery Pressure as Long-Term Mortality Predictor in Elderly Critically Ill with Severe COVID-19 Pneumonia.Viruses · 2025Article
- Predicting prognosis of sepsis in patients based on right ventricular strain imaging development and validation of a nomogram model.Frontiers in cardiovascular medicine · 2025Article
- Non-invasive surrogates for right Ventricular-Pulmonary arterial coupling: a systematic review and Meta-Analysis.Pulmonary circulation · 2024Article
- The value of right ventricular pulmonary artery coupling in determining the prognosis of patients with sepsis.Scientific reports · 2024Article
- Echocardiographic features of right ventricle in septic patients with elevated central venous pressure.BMC anesthesiology · 2024Article
- Assessment of Pulmonary Circulation of Critically Ill Patients Based on Critical Care Ultrasound.Journal of clinical medicine · 2024Review
- The value of right ventricular to pulmonary arterial coupling in the critically ill: a National Echocardiography Database of Australia (NEDA) substudy.Annals of intensive care · 2024Article
- The tricuspid annular plane systolic excursion/PASP ratio's accuracy and validity in assessing the right ventricular function: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Review
- Tricuspid annular plane systolic excursion/mitral annular plane systolic excursion ratio in critically ill patients: an index of right- and left-ventricular function mismatch and a risk factor for cardiogenic pulmonary edema.BMC anesthesiology · 2023Observational
- Prognostic implication of a novel right ventricular injury score in septic patients.ESC heart failure · 2023Article
- Right ventricular outflow tract Doppler flow analysis and pulmonary arterial coupling by transthoracic echocardiography in sepsis: a retrospective exploratory study.Critical care (London, England) · 2022Article
- Sepsis-related cardiomyopathy: Not an easy task for ICU physicians.Journal of intensive medicine · 2022Review
- Prevalence and prognostic value of various types of right ventricular dysfunction in mechanically ventilated septic patients.Annals of intensive care · 2021Article
- Right Ventricular Dysfunction Score in the Prognostic Evaluation of Patients with Sepsis and Septic Shock.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care MedicineArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo explore the association between the ratio of tricuspid annular plane systolic excursion (TAPSE) and pulmonary arterial systolic pressure (PASP), and long- and short-term outcomes in mechanically ventilated septic shock patients.
methodsSeptic shock patients admitted to the intensive care unit (ICU) were screened for enrollment. Echocardiographic parameters including TAPSE and tricuspid regurgitation velocity, haemodynamic and respiratory parameters, and prognostic data were obtained.
resultsOne hundred eighteen subjects were enrolled in this study, among whom 75 survived and 43 died at the one-year follow-up. ROC curve analysis revealed that the TAPSE/PASP ratio was able to assess one-year all-cause mortality with an area under the curve of 0.817 (95% CI: 0.739-0.896, p < 0.001) and the optimal cutoff value was 0.50 mm/mmHg. Kaplan-Meier survival analysis showed that one-year all-cause mortality was significantly higher in patients with TAPSE/PASP ≤0.5 mm/mmHg than in patients with TAPSE/PASP > 0.5 mm/mmHg (log-rank 32.934, p < 0.001). According to the Cox regression survival analyses, the TAPSE/PASP ratio was independently associated with one-year all-cause mortality (HR 0.007, 95% CI:0.000-0.162, p = 0.002) and ICU mortality (HR 0.027, 95% CI:0.001-0.530, p = 0.017). According to the multivariable analysis, the TAPSE/PASP ratio was an independent variable associated with mechanical ventilation (MV) duration (standard coefficient - 0.240, p = 0.010).
conclusionThe TAPSE/PASP ratio demonstrated prognostic value for one-year all-cause mortality, ICU mortality and MV duration in mechanically ventilated septic shock patients.
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