Evidence map›Paper›PMID 32532294›Full record

ArticleAIDS research and therapy2020

The HIV care continuum and HIV-1 drug resistance among female sex workers: a key population in Guinea-Bissau.

Jacob Lindman, Mamadu Aliu Djalo, Ansu Biai, Fredrik Månsson, Joakim Esbjörnsson, Marianne Jansson, Patrik Medstrand, Hans Norrgren, SWEGUB CORE group

Open access · goldAbstract read
In one paragraph

Article in AIDS research and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Jacob LindmanThe Department of Clinical Sciences Lund, Lund University, Infektionskliniken Skånes Universitetssjukhus Lund, Hälsogatan 3, 221 85, Lund, Sweden. jacob.lopatko_lindman@med.lu.se.ORCID 0000-0002-2034-464X
Mamadu Aliu DjaloEnvironmental Action in the Third World (ENDA), Bissau, Guinea-Bissau.
Ansu BiaiThe National Public Health Laboratory, Bissau, Guinea-Bissau.
Fredrik MånssonThe Department of Translational Medicine, Lund University, Malmö, Sweden.
Joakim EsbjörnssonThe Department of Translational Medicine, Lund University, Malmö, Sweden.
Marianne JanssonThe Department of Laboratory Medicine, Lund University, Lund, Sweden.
Patrik MedstrandThe Department of Translational Medicine, Lund University, Malmö, Sweden.
Hans NorrgrenThe Department of Clinical Sciences Lund, Lund University, Infektionskliniken Skånes Universitetssjukhus Lund, Hälsogatan 3, 221 85, Lund, Sweden.
SWEGUB CORE group
Lund University · SENational Institute of Public Health · GWEnvironment and Development Action Third World · SN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFemale sex workers (FSW) are considered a key group for HIV transmissions in sub-Saharan Africa. The HIV Care Continuum and HIV drug resistance (HIVDR) among FSW has not been well studied in most countries in West Africa. In the current study we describe the HIV Care continuum and prevalence of HIVDR among FSW in Guinea-Bissau.

methodsA venue-based recruitment and peer-referral of FSW was used in seven cities in Guinea-Bissau from October 2014 to September 2017. We administered a questionnaire, performed discriminatory HIV-testing and collected blood specimens for CD4 count, viral load and HIVDR genotyping.

resultsThe survey included 440 FSW. The overall HIV-prevalence among FSW was 26.8%. Of the HIV-1 (HIV-1 single- or dually HIV-1/HIV-2) infected FSW (N = 104), 58.7% were previously diagnosed with HIV-1 at enrolment and 41.4% reported taking antiretroviral therapy (ART) compared to 28.6% of the HIV-2 single-infected FSW (N = 14). Among HIV-1 infected FSW on ART (N = 43), 55.8% were virally suppressed (< 1000 copies/ml) and of all HIV-1 infected FSW, 29.8% were virally suppressed. Among ART experienced FSW (N = 22), 50.0% had HIVDR. HIVDR was also found in 9.4% of treatment naïve FSW (N = 53).

conclusionThe majority of FSW who knew their HIV status received ART, however a large proportion of FSW were not aware of their HIV positive status. This translated into a great majority of the HIV-infected FSW not being virally suppressed. Amongst treatment naïve FSW nearly a tenth had HIVDR, suggesting that sexual transmission of HIVDR is occurring in this at-risk-population.

Indexed as

Continuity of Patient CareDrug Resistance, ViralAdultAnti-HIV AgentsCD4 Lymphocyte CountCross-Sectional StudiesFemaleGuinea-BissauHIV-1HIV InfectionsHumansMiddle AgedPrevalenceSex WorkersSurveys and QuestionnairesViral LoadAnti-HIV AgentsAfricaAntiretroviral therapyDrug resistance mutationsHIV care continuumHIV seroprevalenceSex workers

Identifiers

PMID32532294
PMCPMC7291728
OpenAlexW3034339352

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.