Evidence map›Paper›PMID 32532283›Full record

ArticleTrials2020

Effectiveness of inspiratory muscle training associated with a cardiac rehabilitation program on sympathetic activity and functional capacity in patients with heart failure: a study protocol for a randomized controlled trial.

Jéssica Costa Leite, Daniella Cunha Brandão, Simone Cristina Soares Brandão, Helen Kerlen Bastos Fuzari, Tainá Maria Vidal, Jasiel Frutuoso, Maria Inês Remígio, Bruna Thays Santana de Araújo, Shirley Lima Campos, Armele Dornelas de Andrade

2 registry-linked trialsAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02600000 naunknown statusnot on this map

Effectiveness of Inspiratory Muscle Training Associated With a Cardiac Rehabilitation Program in Sympathetic Activity and Functional Capacity in Patients With Heart Failure: a Randomized Clinical Trial

TypeinterventionalSponsorUniversidade Federal de PernambucoRan2015 to 2020Enrolled20ConditionsHeart FailureArmsMyocardial scintigraphy, Cardiopulmonary test, AVD-Glittre Test, Diaphragm ultrasound
NCT05005702 nacompletednot on this map

Effects of Inspiratory Muscle Training on Functional Capacity in Patients With Heart Failure

TypeinterventionalSponsorRiphah International UniversityRan2020 to 2021Enrolled16ConditionsHeart FailureArmsInspiratory Muscle training
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jéssica Costa LeiteDepartment of Physiotherapy, Universidade Federal do Rio Grande do Norte, Av. Senador Salgado Filho, s/n, Natal, 59078-970, Rio Grande do Norte, Brazil.
Daniella Cunha BrandãoDepartment of Physiotherapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Recife, Pernambuco, 50740-560, Brazil. daniellacunha@hotmail.com.
Simone Cristina Soares BrandãoNuclear Medicine and Cardiology Services, Hospital das Clínicas de Pernambuco, Universidade Federal de Pernambuco, Av. Prof. Moraes Rego, 1235, Recife, 50670-901, Pernambuco, Brazil.
Helen Kerlen Bastos FuzariDepartment of Physiotherapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Recife, Pernambuco, 50740-560, Brazil.
Tainá Maria VidalDepartment of Physiotherapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Recife, Pernambuco, 50740-560, Brazil.
Jasiel FrutuosoDepartment of Physiotherapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Recife, Pernambuco, 50740-560, Brazil.
Maria Inês RemígioDepartment of Clinical Semiology of the Medicine Faculty, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Cidade Universitária, Recife, 50740-560, Pernambuco, Brazil.
Bruna Thays Santana de AraújoDepartment of Physiotherapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Recife, Pernambuco, 50740-560, Brazil.
Shirley Lima CamposDepartment of Physiotherapy, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s / n, Recife, Pernambuco, 50740-560, Brazil.
Armele Dornelas de AndradeDepartment of Physiotherapy, Universidade Federal do Rio Grande do Norte, Av. Senador Salgado Filho, s/n, Natal, 59078-970, Rio Grande do Norte, Brazil.

Funding

FACEPE Edital Multiusuário APQ 0154-4.08/15
6 · The paper itself

Abstract

backgroundIndividuals affected by heart failure (HF) may present fatigue, dyspnea, respiratory muscle weakness, and sympathetic activity hyperstimulation of the myocardium, among other symptoms. Conducting cardiac rehabilitation (CR) programs can be associated with inspiratory muscle training. The aim of this study was to evaluate the efficacy of inspiratory muscular training (IMT) associated with a CR program on modulating myocardial sympathetic activity and maximal functional capacity, submaximal functional capacity, thickness, and mobility of the diaphragm muscle in patients with HF.

methodsWe will conduct a clinical, controlled, randomized, double-blind trial that will include sedentary men and women who are 21-60 years old and who have diagnosed systolic HF and a left ventricular ejection fraction of less than 45%. Participants will be randomly assigned to one of two groups: experimental and control. The control group will follow the conventional CR protocol, and the experimental group will follow the conventional CR protocol associated with IMT 7 days a week. The two proposed exercise protocols will have a frequency of three times a week for a period of 12 weeks. The sympathetic innervation of the cardiac muscle, the maximum and submaximal functional capacity, diaphragm mobility and thickness, and the quality of life of the participants will be evaluated before and after the intervention protocol. DISCUSSION: This clinical trial will be the first study to investigate the additional effects of IMT on CR in sympathetic hyperstimulation in the myocardium. The results of this study will contribute to developing therapeutic strategies collaborating to elucidate whether the association of IMT with CR can induce clinical benefits for patients with HF.

trial registrationClinicalTrials.gov identifier: NCT02600000. Registered November 9, 2015. Retrospectively registered.

Indexed as

BrazilBreathing ExercisesCardiac RehabilitationDouble-Blind MethodExercise TherapyHeart FailureHumansMuscle StrengthQuality of LifeRandomized Controlled Trials as TopicRespiratory MusclesStroke VolumeVentricular Function, LeftCardiac rehabilitationFunctional capacityHeart failureInspiratory muscle trainingSympathetic hyperactivation

Identifiers

PMID32532283
PMCPMC7291458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.