Evidence map›Paper›PMID 32532276›Full record

ArticleBMC geriatrics2020

Using the Drug Burden Index to identify older adults at highest risk for medication-related falls.

Susan J Blalock, Chelsea P Renfro, Jessica M Robinson, Joel F Farley, Jan Busby-Whitehead, Stefanie P Ferreri

Abstract read
In one paragraph

Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susan J BlalockDivision of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, CB# 7573, USA. s_blalock@unc.edu.ORCID 0000-0002-8750-3385
Chelsea P RenfroDepartment of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center College of Pharmacy, Memphis, USA.
Jessica M RobinsonDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Joel F FarleyDepartment of Pharmaceutical Care & Health Systems, University of Minnesota College of Pharmacy, Minneapolis, USA.
Jan Busby-WhiteheadDivision of Geriatric Medicine and Director, Center of Aging and Health, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Stefanie P FerreriDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, USA.

Funding

Implementing an Integrative Falls Prevention Program for High-Risk Patients in Community PharmaciesU01CE002769 · CE · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BLALOCK, SUSAN J, FERRERI, STEFANIE P · 2016 to 2018
$1.1M
CDC HHS 1 U01 CE002769-01Centers for Medicare and Medicaid Services 1C1CMS331338NCIPC CDC HHS U01 CE002769
6 · The paper itself

Abstract

backgroundThe Drug Burden Index (DBI) was developed to assess patient exposure to medications associated with an increased risk of falling. The objective of this study was to examine the association between the DBI and medication-related fall risk.

methodsThe study used a retrospective cohort design, with a 1-year observation period. Participants (n = 1562) were identified from 31 community pharmacies. We examined the association between DBI scores and four outcomes. Our primary outcome, which was limited to participants who received a medication review, indexed whether the review resulted in at least one medication-related recommendation (e.g., discontinue medication) being communicated to the participant's health care provider. Secondary outcomes indexed whether participants in the full sample: (1) screened positive for fall risk, (2) reported 1+ falls in the past year, and (3) reported 1+ injurious falls in the past year. All outcome variables were dichotomous (yes/no).

resultsAmong those who received a medication review (n = 387), the percentage of patients receiving at least one medication-related recommendation ranged from 10.2% among those with DBI scores of 0 compared to 60.2% among those with DBI scores ≥1.0 (Chi-square (4)=42.4, p < 0.0001). Among those screened for fall risk (n = 1058), DBI scores were higher among those who screened positive compared to those who did not (Means = 0.98 (SD = 1.00) versus 0.59 (SD = 0.74), respectively, p < 0.0001).

conclusionOur findings suggest that the DBI is a useful tool that could be used to improve future research and practice by focusing limited resources on those individuals at greatest risk of medication-related falls.

Indexed as

Accidental FallsPharmaceutical PreparationsAgedCholinergic AntagonistsHumansHypnotics and SedativesRetrospective StudiesCholinergic AntagonistsHypnotics and SedativesPharmaceutical PreparationsAccidental fallsAgingHealth servicesMedicationMedication therapy management

Identifiers

PMID32532276
PMCPMC7291506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.