Evidence map›Paper›PMID 32532215›Full record

ArticleBMC genomics2020

Genomic variation between PRSV resistant transgenic SunUp and its progenitor cultivar Sunset.

Jingping Fang, Andrew Michael Wood, Youqiang Chen, Jingjing Yue, Ray Ming

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jingping FangThe Public Service Platform for Industrialization Development Technology of Marine Biological Medicine and Product of State Oceanic Administration, Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, 350117, Fujian, China.
Andrew Michael WoodDepartment of Plant Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Youqiang ChenThe Public Service Platform for Industrialization Development Technology of Marine Biological Medicine and Product of State Oceanic Administration, Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, 350117, Fujian, China.
Jingjing YueFAFU and UIUC-SIB Joint Center for Genomics and Biotechnology, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, China.
Ray MingFAFU and UIUC-SIB Joint Center for Genomics and Biotechnology, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian, China. rming@life.uiuc.edu.ORCID http://orcid.org/0000-0002-9417-5789
Fujian Normal University · CNUniversity of Illinois Urbana-Champaign · USFujian Agriculture and Forestry University · CN

Funding

National Science Foundation DBI-1546890Natural Science Foundation of Fujian Province 2018J01601Natural Science Foundation of Fujian Province 2019J0102
6 · The paper itself

Abstract

backgroundThe safety of genetically transformed plants remains a subject of scrutiny. Genomic variants in PRSV resistant transgenic papaya will provide evidence to rationally address such concerns.

resultsIn this study, a total of more than 74 million Illumina reads for progenitor 'Sunset' were mapped onto transgenic papaya 'SunUp' reference genome. 310,364 single nucleotide polymorphisms (SNPs) and 34,071 small Inserts/deletions (InDels) were detected between 'Sunset' and 'SunUp'. Those variations have an uneven distribution across nine chromosomes in papaya. Only 0.27% of mutations were predicted to be high-impact mutations. ATP-related categories were highly enriched among these high-impact genes. The SNP mutation rate was about 8.4 × 10

conclusionsComparative whole-genome analyses between 'SunUp' and 'Sunset' provide a reliable estimate of genome-wide variations and evidence of organelle-to-nucleus transfer of DNA associated with biolistic transformation.

Indexed as

PotyvirusBiolisticsCaricaDisease ResistanceGenes, PlantGenomicsMutagenesis, InsertionalPlant DiseasesPlants, Genetically ModifiedPolymorphism, Single NucleotideSequence DeletionTransformation, GeneticWhole Genome SequencingCarica papaya L.Genomic variationNuclear mitochondria DNA (NUMT)Nuclear plastid DNA (NUPT)Whole-genome resequencing

Identifiers

PMID32532215
PMCPMC7291442
OpenAlexW3035715940

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.